Different progression rates for deep white matter hyperintensities in elderly men and women
Different progression rates for deep white matter hyperintensities in elderly men and women
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DOI：
10.1212/01.wnl.0000143058.40388.44
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发表时间：
2004-11-09
期刊：
影响因子：
9.9
通讯作者：
van Buchem, MA
中科院分区：
文献类型：
--
作者：
van den Heuvel, DMJ;Admiraal-Behloul, F;van Buchem, MA
作者调查了大量老年男性和女性中白色高信号（WMH）的进展。经过3年的随访，女性的深层WMH（DWMH）大约是男性的两倍。室周WMH的进展对于男性和女性是相同的。性别差异可能会影响DWMH的发病机制，这反过来又可能导致不同的临床后果的妇女。
The authors investigated the progression of white matter hyperintensities (WMHs) in a large population of elderly men and women. After 3 years of follow-up, women had accumulated approximately twice as much deep WMH (DWMH) as men. The progression of periventricular WMH was the same for men and women. Gender differences may affect the pathogenesis of DWMH, which in turn may result in different clinical consequences in women.