Comparison of various assay systems for prostate-specific antigen standardization.
Comparison of various assay systems for prostate-specific antigen standardization.
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前列腺特异性抗原标准化的各种测定系统的比较。
DOI：
10.1093/oxfordjournals.jjco.a039585
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发表时间：
1992
影响因子：
2.4
通讯作者：
Jun Shimazaki
中科院分区：
文献类型：
--
作者：
Manabu Kuriyama;Susumu Akimoto;Hideyuki Akaza;Yoichi Arai;Michiyuki Usami;Kyoichi Imai;Yoshinori Tanaka;Haruki Yamazaki;Yukimichi Kawada;Kenkichi Koiso;Osamu Yoshida;Toshihiko Kotake;H. Yamanaka;Toyohei Machida;Yoshio Aso;Jun Shimazaki
To avoid confusion between serum prostate-specific antigen (PSA) values among various assay systems, clinical studies on the possibility of conversion among detection values were performed. The assay kits used for the PSA comparisons were MARKIT-F PA, MARKIT-M PA, EIKEN PA, PA test WAKO, Ball ELSA PSA, E-Test Tosoh II PA, PROS-CHECK PSA, DELFIA PSA and TANDEM-R PSA. Using each kit, the standards attached to each assay system were detected, and 142 sera samples from benign hypertrophies or prostate cancers were assayed for serum PSA values.通过检测每个试剂盒的标准品，获得的斜率与原始测定系统获得的斜率几乎相同。 The coefficients of correlation among the PSA detection systems, using patients' sera, were very high, and linear regression lines were also obtained. The results suggest that almost identical serum PSA values may be detected either by multiplying by a coefficient to bring it to the standard or using the conversion formula.
To avoid confusion between serum prostate-specific antigen (PSA) values among various assay systems, clinical studies on the possibility of conversion among detection values were performed. The assay kits used for the PSA comparisons were MARKIT-F PA, MARKIT-M PA, EIKEN PA, PA test WAKO, Ball ELSA PSA, E-Test Tosoh II PA, PROS-CHECK PSA, DELFIA PSA and TANDEM-R PSA. Using each kit, the standards attached to each assay system were detected, and 142 sera samples from benign hypertrophies or prostate cancers were assayed for serum PSA values. By detecting the standards for each kit, slopes were obtained which were almost identical to those obtained from original assay system. The coefficients of correlation among the PSA detection systems, using patients' sera, were very high, and linear regression lines were also obtained. The results suggest that almost identical serum PSA values may be detected either by multiplying by a coefficient to bring it to the standard or using the conversion formula.