Preoperative needle biopsy and immunohistochemical analysis for gastrointestinal stromal tumor of the rectum mimicking vaginal leiomyoma
Preoperative needle biopsy and immunohistochemical analysis for gastrointestinal stromal tumor of the rectum mimicking vaginal leiomyoma
复制标题
类似阴道平滑肌瘤的直肠胃肠道间质瘤的术前穿刺活检和免疫组化分析
DOI：
10.1136/ijgc-00009577-200603000-00078
复制
发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Yoshihiro Kikuchi
中科院分区：
文献类型：
--
作者：
Masashi Takano;Keiko Saito;Tsunekazu Kita;Kenichi Furuya;Shinsuke Aida;Yoshihiro Kikuchi
胃肠道间质瘤（GIST）的术前诊断准确率约为50%。术前评估对育龄妇女盆腔肿瘤的治疗至关重要。我们报告了第一例直肠胃肠道间质瘤，术前经阴道壁穿刺活检确诊。该病例为一名38岁女性，有生殖器出血史。内科检查显示左侧盆腔内有一圆形弹性肿块（7 × 7 cm）。使用手动操作的活检针从阴道左侧壁的活检标本显示出对CD 34和CD 117（c-KIT）的强烈反应。患者接受了直肠低位前切除术、肿瘤切除术和后阴道部分切除术。术前经阴道穿刺活检对不明原因和恶性潜能的盆腔肿瘤有较高的诊断价值。
Accurate preoperative diagnosis for gastrointestinal stromal tumor (GIST) was obtained using the endoscopic approach in about 50% of the cases. Preoperative assessment is quite important in reproductive women for the treatment of pelvic tumor. We report the first case of GIST of the rectum that was accurately diagnosed with preoperative needle biopsy from the vaginal wall. The case was a 38-year-old woman who presented with a history of genital bleeding. Internal examination revealed a round and elastic mass (7 × 7 cm) in the left pelvic cavity. The biopsy specimen from the left sidewall of the vagina using a manually manipulated biopsy needle showed strong reaction for CD34 and CD117 (c-KIT). The patient underwent low anterior resection of the rectum, tumor resection, and partial resection of the posterior vagina. Preoperative biopsy with vaginal approach might be helpful to make a diagnosis for pelvic tumor of unknown origin and unknown malignant potential.