Intraoperative oculomotor nerve monitoring predicts outcome following clipping of posterior communicating artery aneurysms

Intraoperative oculomotor nerve monitoring predicts outcome following clipping of posterior communicating artery aneurysms
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DOI:
10.1016/j.jocn.2011.07.048
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发表时间:
2012-05-01
影响因子:
2
通讯作者:
Jiang, Yugang
Jiang, Yugang
中科院分区:
医学4区
文献类型:
--
作者:
Zhou, Qian;Zhang, Mingming;Jiang, Yugang

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不存在预测术中动眼神经麻痹(ONP、上睑下垂和/或复视)的有效参数。在涉及46名后交通动脉瘤患者的49例手术中,动脉瘤夹闭后刺激动眼神经。对提上睑肌 (LPS) 肌肉诱发的复合肌肉动作电位 (CMAP) 参数(刺激阈值、幅度和潜伏期)进行定量分析。 CMAP 振幅的绝对值与术后初始和长期动眼神经功能 (ONF) 具有统计学相关性 (p < 0.05)。此外,蛛网膜下腔出血 (SAH) 显着影响 CMAP 阈值 (p < 0.05)。监测 LPS 肌肉活动对于评估 ONF 很有价值,LPS 的 CMAP 幅度可能是 ONF 的可靠预测因子。此外,SAH对LPS CMAP的参数有影响。 (C) 2011 Elsevier Ltd. 保留所有权利。
Valid parameters do not exist to predict oculomotor nerve palsy (ONP, ptosis and/or diplopia) intraoperatively. In 49 operations involving 46 patients with posterior communicating artery aneurysms, the oculomotor nerves were stimulated after the aneurysms were clipped. A quantitative analysis of evoked compound muscle action potential (CMAP) parameters (stimulus threshold, amplitude and latency) from the levator palpebrae superioris (LPS) muscle was performed. Absolute values of CMAP amplitude statistically correlated with initial and long-term oculomotor nerve function (ONF) after surgery (p < 0.05). In addition, subarachnoid hemorrhage (SAH) significantly influenced the CMAP threshold (p < 0.05). Monitoring of LPS muscle activity is valuable in the assessment of ONF, and the CMAP amplitude of LPS may be a reliable predictor of ONF. Moreover, SAH has an impact on the parameters of the LPS CMAP. (C) 2011 Elsevier Ltd. All rights reserved.