Aggression-associated changes in murine olfactory tubercle bioamines
Aggression-associated changes in murine olfactory tubercle bioamines
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DOI：
10.1016/s0006-8993(02)03963-x
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发表时间：
2003-02-14
期刊：
影响因子：
2.9
通讯作者：
Garris, DR
中科院分区：
文献类型：
--
作者：
Garris, DR
The relationship between changes in regional brain bioamine levels and the expression of intraspecies aggressive behavior was evaluated in two murine models. In one study, normal male mice were maintained either in aggregate (i.e., normal, intraspecies social behavioral controls) or isolated (i.e., developed, non-social intraspecies aggressive 'fighter' behavior) housing environments, and the accompanying changes in both olfactory tubercle (OT) and hypothalamic (HYPOTH), norepinephrine (NE), dopamine (DA) and serotonin (5-HT) concentration indices quantitated by high-performance liquid chromatography (HPLC) for analysis of behavior-related alterations in localized bioamine deposition loci. Intact mice which had been housed in isolation cages and which exhibited aggressive, intraspecies reflexive-biting ('fighter') behavior when introduced to a novel (stimulus) animal, exhibited significant (P
