Modern Anesthetic Ethers Demonstrate Quantum Interactions with Entangled Photons
Modern Anesthetic Ethers Demonstrate Quantum Interactions with Entangled Photons
复制标题
DOI：
10.1038/s41598-019-47651-1
复制
发表时间：
2019-08-05
影响因子：
4.6
通讯作者：
Goodson, Theodore, III
中科院分区：
文献类型：
--
作者：
Burdick, Ryan K.;Villabona-Monsalve, Juan P.;Goodson, Theodore, III
尽管经过了几十年的研究，麻醉剂诱导的无意识的机制仍然不完全清楚，一些人倡导量子力学基础。尽管全身麻醉与电子自旋等物理性质的变化有关，但还没有经验证明全身麻醉剂能够进行功能性的量子相互作用。在这项工作中，我们用UV-Vis光谱、含时密度泛函理论(TD-DFT)计算、经典双光子光谱和纠缠双光子光谱研究了卤代醚七氟醚(SEVO)和异氟醚(ISO)的线性和非线性光学性质。我们发现这两个卤代醚都与800 nm纠缠光子对相互作用，但都不与800 nm经典光子相互作用。相比之下，非卤代乙醚不与纠缠的光子相互作用。这是卤化麻醉药可以直接进行量子相互作用机制的第一个实验证据，为理解其物理化学性质提供了新的途径。
Despite decades of research, the mechanism of anesthetic-induced unconsciousness remains incompletely understood, with some advocating for a quantum mechanical basis. Despite associations between general anesthesia and changes in physical properties such as electron spin, there has been no empirical demonstration that general anesthetics are capable of functional quantum interactions. In this work, we studied the linear and non-linear optical properties of the halogenated ethers sevoflurane (SEVO) and isoflurane (ISO), using UV-Vis spectroscopy, time dependent-density functional theory (TD-DFT) calculations, classical two-photon spectroscopy, and entangled two-photon spectroscopy. We show that both of these halogenated ethers interact with pairs of 800 nm entangled photons while neither interact with 800 nm classical photons. By contrast, nonhalogenated diethyl ether does not interact with entangled photons. This is the first experimental evidence that halogenated anesthetics can directly undergo quantum interaction mechanisms, offering a new approach to understanding their physicochemical properties.