Physical activity and cognitive health
Physical activity and cognitive health
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DOI：
10.1016/j.jalz.2007.01.009
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发表时间：
2007-04-01
影响因子：
14
通讯作者：
Trojanowski, John Q.
中科院分区：
文献类型：
--
作者：
Jedrziewski, A. Kathryn;Lee, Virginia M. -Y.;Trojanowski, John Q.
背景：工业化国家正在经历一场人口革命，其原因是寿命的持续延长和65岁以上人口比例的迅速上升。促进健康老龄化的干预措施将继续具有重要意义，因为努力延缓残疾和功能丧失的强度。方法：由于体育活动与促进健康老龄化有关，在这里我们回顾了大量关于体育活动和认知健康的研究。具体而言，我们关注体育活动与认知功能和痴呆的关联，包括预防、延迟或减缓疾病进展。因此，我们准备了一份描述性文献综述，包括自1999年以来在同行评议期刊上发表的各种类型的出版物、前瞻性队列、病例对照、临床试验和荟萃分析文章。结果：根据现有的数据，我们得出结论，在体力活动的个体中，随着年龄的增长，认知能力下降的相对风险可能会降低；然而，到目前为止，这还没有得到明确的证明。结论：需要进一步的研究来确定体力活动对认知功能和痴呆的决定性影响，并阐明这种联系的基础。(c) 2007年阿尔茨海默病协会。版权所有。
Background: The industrialized nations are experiencing a demographic revolution caused by the continuing increase in longevity and the rapid rise in the percentage of the population older than 65 years. Interventions that promote healthy aging will continue to gain significance as efforts to delay disability and loss of function intensity.Methods: Because physical activity has been implicated in promoting healthy aging, here we review a large body of research that examines physical activity and cognitive health. Specifically, we focus on the associations of physical activity with cognitive function and dementia, including prevention, delay, or slowing down of disease progression. Thus, we have prepared a descriptive review of the literature including various types of publications, prospective cohort, case-control, clinical trial, and meta-analysis articles published since 1999 in peer-reviewed journals.Results: On the basis of currently available data, we conclude that the relative risk of cognitive decline with aging might diminish in individuals who are physically active; however, this has not been definitively demonstrated thus far.Conclusions: Further research is needed to determine conclusively the effects of physical activity on cognitive function and dementia and to elucidate the basis for this linkage. (c) 2007 The Alzheimer's Association. All rights reserved.