The prevalence and types of glaucoma in Malay people: The Singapore Malay Eye Study
The prevalence and types of glaucoma in Malay people: The Singapore Malay Eye Study
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DOI：
10.1167/iovs.08-1759
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发表时间：
2008-09-01
影响因子：
4.4
通讯作者：
Aung, Tin
中科院分区：
文献类型：
--
作者：
Shen, Sunny Y.;Wong, Tien Y.;Aung, Tin
目的。评估亚洲马来人人群中青光眼的患病率和类型。方法：新加坡马来人眼科研究是一项以人群为基础的横断面调查，调查了3280名年龄在40岁到80岁之间的人(78.7%的受访者)。参与者接受了标准化的临床检查，包括裂隙灯生物显微镜、Goldmann压平眼压测量和视盘扩张评估。怀疑患有青光眼的受试者还接受了视野检查(24-2SITA标准，Humphrey视野分析仪II)、房角镜和重复平压眼压测量。结果：在3280名参与者中，150名(4.6%)被诊断为青光眼，年龄和性别标化患病率为3.4%(95%可信区间[CI]，3.3%-3.5%)。年龄和性别标化的原发性开角型青光眼患病率为2.5%(95%CI，2.4%~2.6%)，原发性闭角型青光眼患病率为0.12%(95%CI，0.10%~0.14%)，继发性青光眼患病率为0.61%(95%CI，0.59%~0.63%)。在150例青光眼病例中，只有12例(8%)有已知的青光眼病史。27只眼(18%)有低视力(根据最小分辨角度的最佳矫正视力对数0.30至1.00在单眼青光眼病例中；在双眼病例中基于较好的眼睛)，15只眼(10%)失明(LogMAR，>；=1.00)。结论：新加坡40岁及以上的马来人青光眼患病率为3.4%，与新加坡和亚洲其他种族/民族的中国人人相当。与中国人、高加索人和非洲人一样，原发性开角型青光眼是这些人群中青光眼的主要形式。超过90%的青光眼病例以前没有被发现。
PURPOSE. To assess the prevalence and types of glaucoma in an Asian Malay population.METHODS. The Singapore Malay Eye Study is a population-based, cross-sectional survey that examined 3280 (78.7% response) persons aged 40 to 80 years. Participants underwent a standardized clinical examination including slit-lamp biomicroscopy, Goldmann applanation tonometry, and dilated optic disc assessment. Participants who were suspected to have glaucoma also underwent visual field examination (24-2 SITA standard, Humphrey Visual Field Analyzer II), gonioscopy, and repeat applanation tonometry. Glaucoma was defined according to International Society for Geographical and Epidemiologic Ophthalmology criteria.RESULTS. Of the 3280 participants, 150 (4.6%) had diagnosed glaucoma, giving an age- and sex-standardized prevalence of 3.4% (95% confidence interval [CI], 3.3%-3.5%). The age- and sex-standardized prevalence of primary open-angle glaucoma was 2.5% ( 95% CI, 2.4%-2.6%), primary angle-closure glaucoma 0.12% ( 95% CI, 0.10%-0.14%), and secondary glaucoma 0.61% ( 95% CI, 0.59%-0.63%). Of the 150 glaucoma cases, only 12 (8%) had a previous known history of glaucoma. Twenty-seven (18%) eyes had low vision ( based on best corrected visual acuity logarithm of the minimal angle of resolution [logMAR] > 0.30 to < 1.00 in the eye with glaucoma for unilateral cases; and based on the better eye for bilateral cases) and 15 (10%) were blind ( logMAR, >= 1.00).CONCLUSIONS. The prevalence of glaucoma among Malay persons 40 years of age and older in Singapore is 3.4%, comparable to ethnic Chinese people in Singapore and other racial/ethnic groups in Asia. As in Chinese, Caucasians, and African people, primary open-angle glaucoma was the main form of glaucoma in this population. More than 90% of glaucoma cases were previously undetected.