On the synthesis and characterization of N-formyl glutathione and N-acetyl glutathione.
On the synthesis and characterization of N-formyl glutathione and N-acetyl glutathione.
复制标题
N-甲酰基谷胱甘肽和N-乙酰基谷胱甘肽的合成与表征。
DOI：
10.1006/abio.1993.1467
复制
发表时间：
1993
影响因子：
2.9
通讯作者：
Meister,A
中科院分区：
文献类型：
--
作者：
Levy,EJ;Anderson,ME;Meister,A
用甲酸和乙酸酐处理谷胱甘肽（GSH）导致制备结晶N-甲酰基GSH。这是N-甲酰GSH的第一个表征制剂;该产品以前被错误地认为是N-乙酰基GSH。通过用乙酸和乙酸酐处理GSH来制备真正的N-乙酰基GSH（结晶）。N-酰化衍生物经1H NMR和质谱表征。
Treatment of glutathione (GSH) with formic acid and acetic anhydride leads to preparation of crystalline N-formyl GSH. This is the first characterized preparation of N-formyl GSH; this product was previously erroneously thought to he N-acetyl GSH. Authentic N-acetyl GSH (crystalline) was prepared by treating GSH with acetic acid and acetic anhydride. The N-acylated derivatives were characterized by1H NMR and mass spectroscopy.