Capuramycin, a new nucleoside antibiotic. Taxonomy, fermentation, isolation and characterization.
Capuramycin, a new nucleoside antibiotic. Taxonomy, fermentation, isolation and characterization.
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Capuramycin，一种新型核苷类抗生素。
DOI：
10.7164/antibiotics.39.1047
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Noboru Otake
中科院分区：
文献类型：
--
作者：
Hiroshi Yamaguchi;Shingo Sato;Shiro Yoshida;Kinji Takada;Masayoshi Itoh;Haruo Seto;Noboru Otake
采用吸附和分配柱层析法，从灰色链霉菌446-S3的培养滤液中分离得到一种新的抗生素卡普霉素。基于其化学结构是具有己内酰胺取代基的尿嘧啶核苷，该物质被命名为卡普霉素。本文介绍了卡普霉素产生菌的分类、发酵、分离、鉴定和生物学特性。
A new antibiotic capuramycin was isolated from the culture filtrate of Streptomyces griseus 446-S3 by adsorption and partition column chromatography. Based on its chemical structure being an uracil nucleoside with a caprolactam substituent, this substance was named as capuramycin. This paper describes the taxonomy of a producing organism, fermentation, isolation, characterization and biological properties of capuramycin.