A portable micro glucose sensor based on copper-based nanocomposite structure
A portable micro glucose sensor based on copper-based nanocomposite structure
复制标题
一种基于铜基纳米复合结构的便携式微葡萄糖传感器
DOI：
10.1039/c9nj00888h
复制
发表时间：
2019-05-28
影响因子：
3.3
通讯作者：
Cui, Guofeng
中科院分区：
文献类型：
--
作者：
Chen, Huang;Fan, Guokang;Cui, Guofeng
精确检测人体内葡萄糖的浓度是预防或治疗糖尿病的一种有吸引力的方法。近年来，采用非酶催化材料的便携式葡萄糖传感器受到了高度关注。在此，提出了一种用于制造高性能电化学传感器的简易策略。设计并制作了一种基于CuO纳米珊瑚阵列/纳米多孔Cu（NCA/NPC）的非酶三电极集成葡萄糖传感器。便携式NCA/NPC葡萄糖传感器装置对葡萄糖具有高催化活性。NCA/NPC葡萄糖传感器器件的优异性能来源于NPC基底的优异导电性和CuO纳米珊瑚阵列的高电催化活性。该装置在0.0005-5.0 mM范围内具有1621 A mM（-1）cm（-2）的高灵敏度、200 nM的低检测限（S/N = 3）、3 s的快速响应时间、良好的抗干扰性能、优良的重复性和相当的稳定性。这一工作将为未来的非酶葡萄糖传感器提供有效的结构和合适的催化材料选择。
Precisely detecting the concentration of glucose in the human body is an attractive way to prevent or treat diabetes. Portable glucose sensors with non-enzymatic catalytic materials have received great attention in recent years. Herein, a facile strategy for fabricating a high-performance electrochemical sensor is proposed. A non-enzymatic three-electrode integrated glucose sensor device based on CuO nano-coral arrays/nanoporous Cu (NCA/NPC) is designed and fabricated. The portable NCA/NPC glucose sensor device exhibits high catalytic activity for glucose. The great performance of the NCA/NPC glucose sensor device derives from the excellent conductivity of the NPC substrate and the high electrocatalytic activity of CuO nano-coral arrays. This device exhibits a high sensitivity of 1621 A mM(-1) cm(-2) in the linear range of 0.0005-5.0 mM, low detection limit of 200 nM (S/N = 3), fast response time of 3 s, good anti-interference performance, excellent repeatability and considerable stability for glucose detection. This work will certainly provide an efficient structure and proper catalytic material choices for future non-enzymatic glucose sensors.