Effects of parabens on apoptosis induced by serum-free medium

Effects of parabens on apoptosis induced by serum-free medium
复制标题

对羟基苯甲酸酯对无血清培养基诱导细胞凋亡的影响

DOI：
10.1080/03601234.2012.634341
复制
发表时间：
2012
期刊：
Journal of Environmental Science and Health
影响因子：
--
通讯作者：
Saito T and Kurasaki M
Saito T and Kurasaki M
中科院分区：
--
文献类型：
--
作者：
Egawa M;Aoki K;Sun Y;Hosokawa T;Saito T and Kurasaki M

文献摘要

相似文献

Alkyl esters ofp-hydroxybenzoic acids (parabens), an endocrine disrupter, are used as preservatives in cosmetics and foods. In this study, to understand the relationship between parabens and differentiation in infants, the effects of parabens on apoptosis induced by serum deprivation in PC12 cells were investigated. In addition, apoptosis-related factors were assayed. As results, a tendency toward enhancement of apoptosis was observed in the cells cultured in the serum-free medium with methylparaben, and this tendency was suggested to be related to the contents of BAD, a pro-apoptotic protein. Butylparaben did not show any tendency to enhance apoptosis.