OPTIMIZATION OF 3-D IMAGE-GUIDED NEAR INFRARED SPECTROSCOPY USING BOUNDARY ELEMENT METHOD.
OPTIMIZATION OF 3-D IMAGE-GUIDED NEAR INFRARED SPECTROSCOPY USING BOUNDARY ELEMENT METHOD.
复制标题
使用边界元法优化 3D 图像引导近红外光谱。
DOI：
10.1109/isbi.2009.5193242
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发表时间：
2009
期刊：
影响因子：
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通讯作者：
Paulsen,KeithD
中科院分区：
文献类型：
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作者：
Srinivasan,Subhadra;Carpenter,Colin;Pogue,BrianW;Paulsen,KeithD
Multimodality imaging systems combining optical techniques with MRI/CT provide high-resolution functional characterization of tissue by imaging molecular and vascular biomarkers. To optimize these hybrid systems for clinical use, faster and automatable algorithms are required for 3-D imaging. Towards this end, a boundary element model was used to incorporate tissue boundaries from MRI/CT into image formation process. This method uses surface rendering to describe light propagation in 3-D using diffusion equation. Parallel computing provided speedup of up to 54% in time of computation. Simulations showed that location of NIRS probe was crucial for quantitatively accurate estimation of tumor response. A change of up to 61% was seen between cycles 1 and 3 in monitoring tissue response to neoadjuvant chemotherapy.
