PDMS 2D optical lens integrated with microfluidic channels: principle and characterization

PDMS 2D optical lens integrated with microfluidic channels: principle and characterization
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DOI:
10.1039/b211280a
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发表时间:
2003-01-01
期刊:
影响因子:
6.1
通讯作者:
Fujii, T
Fujii, T
中科院分区:
工程技术1区
文献类型:
--
作者:
Camou, S;Fujita, H;Fujii, T

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本文报道了PDMS二维光学透镜的制备和表征。设计这些透镜是为了提高使用光纤在便携式芯片上执行的荧光光谱检测的性能。首先详细描述了PDMS层的制造过程,然后用SEM检查图案。通过比较各种界面结构,它表明,从光纤出来的光的光束特性可以修改取决于透镜曲率半径。因此,对于恒定的染料浓度,与具有平坦界面的相同设计相比,使用这种透镜可以增加靠近纤维或远离纤维的荧光响应的强度。对应于来自染料的更强响应的这种激发改善随后导致用于荧光光谱的芯片上检测方法的大约三倍的更高灵敏度。
In this paper, the fabrication and characterization of PDMS 2D-optical lenses are reported. These lenses are designed in order to improve the performance of fluorescent spectroscopy detection performed on a portable chip using optical fibers. The fabrication process of the PDMS layer is first detailed, and the patterns are then checked with a SEM. By comparing various interfacial structures, it is shown that the beam properties of the light coming out from the fiber can be modified depending on the lens curvature radius. As a consequence, for a constant dye concentration, the use of such lenses can increase the intensity of fluorescent response close to the fiber or far from the fiber, compared to the same design with a flat interface. This excitation improvement corresponding to a stronger response from the dye then consequently leads to around three times higher sensitivity of the on-chip detection method for fluorescent spectroscopy.