Embolization of the nidus of brain arteriovenous malformations with n-butyl cyanoacrylate
Embolization of the nidus of brain arteriovenous malformations with n-butyl cyanoacrylate
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DOI：
10.1097/00006123-199701000-00026
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发表时间：
1997-01-01
期刊：
影响因子：
4.8
通讯作者：
Dujovny, M
中科院分区：
文献类型：
--
作者：
Debrun, GM;Aletich, V;Dujovny, M
目的：证明使用组织丙烯（B. Braun，Melsungen，德国）是有效的，并产生低发病率和死亡率rates.METHODS：我们提出了一个回顾性分析54脑AVM治疗在伊利诺伊大学芝加哥从1994年4月至1995年12月。治疗方式包括栓塞在所有情况下，然后手术切除或radiosurgery.INSTRUMENTATION：病灶达到与Magic微导管（诱饵，蒙特莫伦西，法国）和Terumo 0.010英寸的guides.Technique的组合使用：栓塞仅在微导管的尖端楔入到病灶的动静脉畸形与近端没有反流的对比。栓塞进行了全身麻醉下，没有Amytal testing.Results：26的54例患者仍在等待更彻底的治疗，同时使用双平面路图与患者。发生了2例死亡和2例轻度和1例重度永久性神经功能缺损。3例单纯栓塞治愈，11例经手术切除治愈。3例患者接受放射外科治疗，1治愈后1 year.CONCLUSION：病灶栓塞与Histoacryl是一种有效的技术，允许完全治愈大量的脑AVM，有或没有手术切除和/或放射外科。
OBJECTIVE: To demonstrate that nidus embolization of brain arteriovenous malformations (AVMs) with Histoacryl (B. Braun, Melsungen, Germany) is effective and yields low morbidity and mortality rates.METHODS: We present a retrospective analysis of 54 brain AVMs treated at the University of Illinois at Chicago from April 1994 to December 1995. Treatment modalities included embolization in all cases and then surgical resection or radiosurgery.INSTRUMENTATION: The nidus was reached with the combined use of a Magic microcatheter (Bait, Montmorency, France) and a Terumo 0.010-inch guidewire.TECHNIQUE: Embolization was performed only when the tip of the microcatheter was wedged into the nidus of the AVMs with no reflux of contrast proximally. The embolization was performed using simultaneous biplane roadmapping with the patient under general anesthesia without Amytal testing.RESULTS: Twenty-six of 54 patients are still waiting for more radical treatment. Two deaths and two minor and one severe permanent neurological deficit occurred. Three patients were cured with embolization alone; 11 patients were cured after surgical resection. Three patients underwent radiosurgery, with one cure after 1 year.CONCLUSION: Nidus embolization with Histoacryl is an effective technique that permits complete cure of a large number of brain AVMs, with or without surgical resection and/or radiosurgery.