Progressive resistance exercise and resting blood pressure - A meta-analysis of randomized controlled trials
Progressive resistance exercise and resting blood pressure - A meta-analysis of randomized controlled trials
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DOI：
10.1161/01.hyp.35.3.838
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发表时间：
2000-03-01
期刊：
影响因子：
8.3
通讯作者：
Kelley, KS
中科院分区：
文献类型：
--
作者：
Kelley, GA;Kelley, KS
高血压是一个主要的公共卫生问题，影响着美国估计4300万平民，非机构化成年人（占该人口的24%）。本研究的目的是使用荟萃分析的方法来检查渐进式抗阻运动对成年人静息收缩压和舒张压的影响。通过（1）计算机化文献检索，（2）原始文献和综述文献的交叉引用，以及（3）由2名运动和血压专家对参考文献列表进行审查，检索研究。入选标准如下：（1）包括随机非运动对照组的试验;（2）渐进式抗阻运动作为唯一干预;（3）成人;（4）在英文文献中发表的期刊文章、论文和硕士论文;（5）1966年1月至1998年12月期间发表和索引的研究;（6）评估静息收缩压和/或舒张压;和（7）持续至少4周的训练研究。在所有设计和类别中，固定效应建模分别使静息收缩压和舒张压降低约2%和4%（平均值+/-SD收缩压，-3 +/-3 mm Hg; 95% bootstrap CI，-4至-1 mm Hg;平均值+/-SD舒张压，-3 +/-2 mm Hg; 95% bootstrap CI，-4至-1 mm Hg）。结论：渐进式抗阻运动对降低成年人静息收缩压和舒张压有效。然而，在确定渐进式抗阻运动作为非药物干预的有效性之前，需要进行额外的研究，限制高血压受试者的入组以及采用意向治疗方法进行数据分析。
Hypertension is a major public health problem affecting an estimated 43 million civilian, noninstitutionalized adults in the United States (24% of this population). The purpose of this study was to use the meta-analytic approach to examine the effects of progressive resistance exercise on resting systolic and diastolic blood pressure in adult humans. Studies were retrieved via (1) computerized literature searches, (2) cross-referencing from original and review articles, and (3) review of the reference list by 2 experts on exercise and blood pressure. Inclusion criteria were as follows: (1) trials that included a randomized nonexercise control group; (2) progressive resistance exercise as the only intervention; (3) adult humans; (4) journal articles, dissertations, and masters theses published in the English-language literature; (5) studies published and indexed between January 1966 and December 1998; (6) resting systolic and/or diastolic blood pressure assessed; and (7) training studies lasting a minimum of 4 weeks. Across all designs and categories, fixed-effects modeling yielded decreases of approximate to 2% and 4% for resting systolic and diastolic blood pressure, respectively (mean+/-SD systolic, -3+/-3 mm Hg; 95% bootstrap CI, -4 to -1 mm Hg; mean+/-SD diastolic, -3+/-2 mm Hg; 95% bootstrap CI, -4 to -1 mm Hg). It was concluded that progressive resistance exercise is efficacious for reducing resting systolic and diastolic blood pressure in adults. However, a need exists for additional studies that limit enrollment to hypertensive subjects as well as analysis of data with an intention-to-treat approach before the effectiveness of progressive resistance exercise as a nonpharmacological intervention can be determined.