Screening asymptomatic patients at high risk for colon cancer with full colonoscopy
Screening asymptomatic patients at high risk for colon cancer with full colonoscopy
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通过全结肠镜检查筛查结肠癌高危无症状患者
DOI：
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发表时间：
1987
影响因子：
3.9
通讯作者：
A. Cohen
中科院分区：
文献类型：
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作者：
Paul VonRyll Gryska;A. Cohen
为了评估仅筛查结肠癌高危患者远端结肠的可靠性，我们回顾了49例完全无症状的结肠镜检查患者的内镜结果，这些患者仅基于结肠癌阳性家族史（平均年龄54.5岁）接受结肠镜检查。息肉样病变31例（63.3%）。13名患者的33个息肉大于1 cm，包括2个浸润性癌。11名患者（22.4%）的息肉仅在近端40 cm，仅在远端肠道检查时无法识别。直肠乙状结肠筛查在这一人群中的预测准确率为78%。结肠癌高危患者的初始筛查应包括完整的结肠镜检查。然后根据内窥镜检查结果确定随访检查的范围。
To evaluate the reliability of screening only the distal colon in patients at high risk for colonic cancer, the endoscopic findings of 49 completely asymptomatic patients who underwent colonoscopy based solely on a positive family history of colonic cancer (average age, 54.5 years) were reviewed. Polypoid lesions were present in 31 (63.3 percent). Thirty-three polyps in 13 patients were large than 1 cm, including two invasive cancers.Eleven patients (22.4 percent) had polyps proximal to 40 cm only and would not have been identified on examination of the distal bowel alone. The predictive accuracy of rectosigmoid screening in this population is 78 percent. Initial screening of patients at high risk for colonic cancer should include full colonoscopy. The extent of follow-up examinations is then based on endoscopic findings.