DrawGlycan-SNFG: a robust tool to render glycans and glycopeptides with fragmentation information
DrawGlycan-SNFG: a robust tool to render glycans and glycopeptides with fragmentation information
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DOI：
10.1093/glycob/cww115
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发表时间：
2017-03-01
期刊：
影响因子：
4.3
通讯作者：
Neelamegham, Sriram
中科院分区：
文献类型：
--
作者：
Cheng, Kai;Zhou, Yusen;Neelamegham, Sriram
聚糖或碳水化合物结构可以使用符号命名法以图形方式表示。聚糖 (SNFG) 的符号命名法包含 67 种不同的单糖，用不同的颜色和几何形状表示。将国际纯粹与应用化学联合会 (IUPAC) 格式文本转换为 SNFG 的简单工具对于绘制聚糖和糖肽非常有用。此类代码还可以开发更复杂的应用程序，其中碳水化合物结构的可视化表示是必要的。为了满足这一需求，当前的手稿描述了 DrawGlycan-SNFG，这是一种免费提供的、独立于平台的开源工具。它允许：显示来自 IUPAC 压缩文本输入的聚糖和糖肽；聚糖和糖肽片段的描述。该程序的在线版本在 www.virtualglume.org/DrawGlycan.Downloadable 上提供了一个用户友好的 Web 界面，独立的 GUI（图形用户界面）版本和程序源代码也可以从此存储库中获得。 DrawGlycan-SNFG 对于正在寻找即用型简单程序来绘制碳水化合物草图的实验人员以及有兴趣将 SNFG 纳入其程序套件的软件开发人员来说非常有用。
Glycan or carbohydrate structures can be pictorially represented using symbolic nomenclatures. The symbol nomenclature for glycans (SNFG) contains 67 different monosaccharides represented using various colors and geometric shapes. A simple tool to convert International Union of Pure and Applied Chemistry (IUPAC) format text to SNFG will be useful for sketching glycans and glycopeptides. Such code can also enable the development of more sophisticated applications, where the visual representation of carbohydrate structures is necessary. To address this need, the current manuscript describes DrawGlycan-SNFG, a freely available, platform-independent, open-source tool. It allows: i. the display of glycans and glycopeptides from IUPAC-condensed text inputs and ii. the depiction of glycan and glycopeptide fragments. The online version of this program is provided with a user-friendly web interface at www.virtualglycome.org/DrawGlycan.Downloadable, stand-alone GUI (Graphical User Interface) version and the program source code are also available from this repository. DrawGlycan-SNFG will be useful for experimentalists looking for a ready to use, simple program for sketching carbohydrates and for software developers interested in incorporating SNFG into their program suite.