SPREAD OF STREPTOCOCCUS-PNEUMONIAE IN FAMILIES .1. CARRIAGE RATES AND DISTRIBUTION OF TYPES
SPREAD OF STREPTOCOCCUS-PNEUMONIAE IN FAMILIES .1. CARRIAGE RATES AND DISTRIBUTION OF TYPES
复制标题
DOI：
10.1093/infdis/132.1.55
复制
发表时间：
1975-01-01
影响因子：
6.4
通讯作者：
GWALTNEY, JM
中科院分区：
文献类型：
--
作者：
HENDLEY, JO;SANDE, MA;GWALTNEY, JM
肺炎链球菌在人与人之间传播的机制尚不清楚。在这项研究中。抽样的最佳方法。s。调查健康携带者的肺炎。分析影响运转率的因素。研究结果包括在成人中咽采样比鼻采样的重要性，小鼠接种比直接血琼脂涂片更敏感，以及与全血清的Quellung反应优于光颏盘作为s的鉴定手段。携带率最高的是学龄前儿童（35%）或小学儿童（29%）以及家庭中有学龄前儿童的成年人（18%）。家庭中没有学龄前儿童的成年人发病率最低（2%-9%）。
The mechanisms by whichStreptococcus pneumoniaespreads from person to person are poorly understood. In this study. optimal methods for sampling. isolation, and identification ofS. pneumoniaefrom healthy carriers were investigated. Factors influencing carriage rates were analyzed. Findings included the importance of pharyngeal rather than of nasal sampling in adults, the greater sensitivity of mouse inoculation compared with direct streaking of blood agar plates, and the superiority of the Quellung reaction with omniserum over the optochin disk as a means of identification ofS. pncumoniae, Carriage rates were highest in children of preschool (35%) or grammar school (29%) age and in adults with preschool children in the family (18%). Rates were lowest in adults without preschool children in the family (2%–9%).