Underlying dimensions of the five health-related quality-of-life measures used in utility assessment: evidence from the National Health Measurement Study.
Underlying dimensions of the five health-related quality-of-life measures used in utility assessment: evidence from the National Health Measurement Study.
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DOI：
10.1097/mlr.0b013e3181e35871
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发表时间：
2010-08
期刊：
影响因子：
3
通讯作者：
Fryback DG
中科院分区：
文献类型：
--
作者：
Cherepanov D;Palta M;Fryback DG
偏好加权的健康相关生活质量（HRQoL）指数从离散的健康状态中产生一个汇总评分，这些健康状态由落入几个属性（如疼痛和移动性）的问题确定。HRQoL值与其他健康结果一起用于监测人群的健康。本研究的目的是在美国成年人中检查HRQoL 5个指标的HRQoL属性得分的基本因素结构：EuroQol-5维度、健康效用指数2分、健康效用指数3分、简明6维度和幸福感量表自我管理表。国家健康测量研究调查了3844名年龄在35至89岁之间居住在美国大陆的非机构化成年人的全国代表性样本。从2005年6月至2006年8月，同时收集了所有5个指数的数据。通过对HRQoL指标属性得分的分类探索性因素分析，探索HRQoL的潜在维度。应用项目反应理论探讨HRQoL属性对潜在维度的信息量贡献。HRQoL的三个主要方面：身体，心理和疼痛。大多数HRQoL指数属性有助于身体或心理方面。3个维度的相关性分别为：0.47（身体和心理社会），0.57（身体和疼痛），0.46（心理社会和疼痛）。一些HRQoL指标属性显示出相对更独特的方差：HUI 3听力、言语和视力，有些对1个以上维度有贡献。确定的因素结构与HRQoL数据拟合良好（比较拟合指数= 0.98，Tucker-Lewis指数= 0.98，近似均方根误差= 0.042）。5个常用HRQoL指标的属性共享HRQoL的3个潜在维度：身体、心理和疼痛。
Preference-weighted health-related quality-of-life (HRQoL) indexes produce a summary score from discrete health states determined by questions falling into several attributes, such as pain and mobility. Values of HRQoL are used alongside other health outcomes to monitor the health of populations. The purpose of this study was to examine among US adults, the underlying factor structure of HRQoL attribute scores across 5 indexes of HRQoL: EuroQol-5 Dimension, Health Utilities Index Mark 2, Health Utilities Index Mark 3, Short Form-6 Dimension, and Quality of Well-Being Scale Self-Administered form. The National Health Measurement Study surveyed a nationally representative sample of 3844 noninstitutionalized adults aged 35 to 89 years residing in the continental US. Simultaneous data on all 5 indexes were collected cross-sectionally from June 2005 to August 2006. Exploration of underlying dimensions of HRQoL was done by categorical exploratory factor analysis of HRQoL indexes' attribute scores. Item response theory was applied to explore the amount of information HRQoL attributes contribute to the underlying latent dimensions. Three main dimensions of HRQoL emerged: physical, psychosocial, and pain. Most HRQoL index attributes contributed to the physical or psychosocial dimension. The 3 dimensions were correlated: 0.47 (physical and psychosocial), 0.57 (physical and pain), 0.46 (psychosocial and pain). Some HRQoL index attributes displayed relatively more unique variance: HUI3 hearing, speech, and vision, and some contributed to more than 1 dimension The identified factor structure fit the HRQoL data well (Comparative Fit Index = 0.98, Tucker-Lewis Index = 0.98, and Root Mean Square Error of Approximation = 0.042). The attributes of 5 commonly used HRQoL indexes share 3 underlying latent dimensions of HRQoL, physical, psychosocial, and pain.