IMMUNOLOGICAL EVALUATION OF PATIENTS WITH POLYCHLORINATED BIPHENYL POISONING - EVALUATION OF DELAYED-TYPE SKIN HYPERSENSITIVE RESPONSE AND ITS RELATION TO CLINICAL-STUDIES
IMMUNOLOGICAL EVALUATION OF PATIENTS WITH POLYCHLORINATED BIPHENYL POISONING - EVALUATION OF DELAYED-TYPE SKIN HYPERSENSITIVE RESPONSE AND ITS RELATION TO CLINICAL-STUDIES
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DOI：
10.1080/15287398209530156
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发表时间：
1982-01-01
期刊：
影响因子：
--
通讯作者：
LEE, TP
中科院分区：
文献类型：
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作者：
CHANG, KJ;HSIEH, KH;LEE, TP
多氯联苯中毒可引起多种生理异常，包括免疫抑制。对30例多氯联苯中毒患者和50例正常人进行了细胞免疫研究。多氯联苯中毒导致细胞免疫抑制，如皮肤对链激酶和链脲酶的延迟型反应。细胞免疫的抑制与疾病的严重程度相关。免疫功能评价有助于多氯联苯中毒的诊断。
Polychlorinated biphenyl (PCB) poisoning causes many physiological abnormalities including immune suppression. Cellular immunity was studied in 30 PCB-poisoned patients and 50 normal subjects. PCB poisoning caused suppression of cellular immunity such as the delayed-type skin response to streptokinase and streptodornase. The suppression of cellular immunity was correlated with the severity of the disease. Evaluation of the immune function may be helpful for the diagnosis of PCB poisoning.