Determination of selected UV filters in indoor dust by matrix solid-phase dispersion and gas chromatography-tandem mass spectrometry
Determination of selected UV filters in indoor dust by matrix solid-phase dispersion and gas chromatography-tandem mass spectrometry
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DOI：
10.1016/j.chroma.2009.06.020
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发表时间：
2009-07-31
影响因子：
4.1
通讯作者：
Cela, R.
中科院分区：
文献类型：
--
作者：
Negreira, N.;Rodriguez, I.;Cela, R.
简单、廉价的样品制备过程。基于基质固相分散 (MSPD) 技术，用于测定六种紫外线过滤剂：水杨酸 2-乙基己酯 (EHS)、水杨酸 3,3,5-三甲基环己酯 (Homosalate, HMS)、3-(4-甲基亚苄基) 樟脑 (4-MBC)、对甲氧基肉桂酸异戊酯 (IAMC)、介绍了室内环境粉尘中的对甲氧基肉桂酸 2-乙基己酯 (EHMC) 和奥克立林 (OCR)，并讨论了几个操作参数对萃取性能的影响。在最终工作条件下，将过筛的样品（0.5 g）与等量的无水硫酸钠混合，并用杵在研钵中与2 g十八烷基键合二氧化硅（C18）分散。将该混合物转移至含有 2 g 活性二氧化硅（作为净化共吸附剂）的聚丙烯固相萃取柱中。首先用 5 mL 正己烷冲洗柱，然后用 4 mL 乙腈回收分析物。将该提取物调节至1mL，过滤并通过气相色谱法结合串联质谱法(GC-MS/MS)测定化合物。添加两种不同浓度的样品的回收率在 77% 到 99% 之间，该方法的定量限 (LOQ) 在 10 到 40 ng g(-1) 之间。不同室内区域沉降灰尘的分析。包括私人公寓、公共建筑和车辆车厢在内的研究表明，EHMC 和 OCR 在该矩阵中普遍存在，最大浓度分别为 15 和 41 mu g g(-1)。这两种紫外线过滤剂还首次在粉尘参考材料 SRM 2585 中进行了定量。在一些分析样品中检测到 EHS、4-MBC 和 IAMC，但浓度低于 EHMC 和 OCR。 (C) 2009 Elsevier B.V. 保留所有权利。
A simple, inexpensive sample preparation procedure. based on the matrix solid-phase dispersion (MSPD) technique, for the determination of six UV filters: 2-ethylhexyl salicylate (EHS), 3,3,5-trimethylcyclohexyl salicylate (Homosalate, HMS), 3-(4-methylbenzylidene) camphor (4-MBC), isoamyl-p-methoxycinnamate (IAMC), 2-ethylhexyl-p-methoxycinnamate (EHMC) and octocrylene (OCR), in dust from indoor environments is presented and the influence of several operational parameters on the extraction performance discussed. Under the final working conditions, sieved samples (0.5 g) were mixed with the same amount of anhydrous sodium sulphate and dispersed with 2 g of octadecyl bonded silica (C18) in a mortar with a pestle. This blend was transferred to a polypropylene solid-phase extraction cartridge containing 2 g of activated silica, as the clean-up co-sorbent. The cartridge was first rinsed with 5 mL of n-hexane and the analytes were then recovered with 4 mL of acetonitrile. This extract was adjusted to I mL, filtered and the compounds were determined by gas chromatography combined with tandem mass spectrometry (GC-MS/MS). Recoveries for samples spiked at two different concentrations ranged between 77% and 99%, and the limits of quantification (LOQs) of the method between 10 and 40 ng g(-1). Analysis of settled dust from different indoor areas. including private flats, public buildings and vehicle cabins, showed that EHMC and OCR were ubiquitous in this matrix, with maximum concentrations of 15 and 41 mu g g(-1), respectively. Both UV filters were also quantified in dust reference material SRM 2585 for first time. EHS, 4-MBC and IAMC were detected in some of the analyzed samples, although at lower concentrations than EHMC and OCR. (C) 2009 Elsevier B.V. All rights reserved.