Determination of optical properties in semi-infinite turbid media using imaging measurements of frequency-domain photon migration obtained with an intensified chargecoupled device

Determination of optical properties in semi-infinite turbid media using imaging measurements of frequency-domain photon migration obtained with an intensified chargecoupled device
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DOI:
10.1117/1.1803549
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发表时间:
2004-11-01
影响因子:
3.5
通讯作者:
Sevick-Muraca, EM
Sevick-Muraca, EM
中科院分区:
医学3区
文献类型:
--
作者:
Gurfinkel, M;Pan, TS;Sevick-Muraca, EM

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通过增强型电荷耦合器件(ICCD)检测系统采集模拟组织半无限体模表面的频域光子迁移测量,并结合扩散近似确定光学特性。当单独或与相对调制幅度数据I-ac(rel)和/或相对相移数据θ(rel)结合使用I-dc(rel)年龄光强度的相对测量时,最不精确地确定吸收和约化散射系数。的吸收和减少散射系数被发现准确到15和11%,分别从标准的单像素测量时,θ(相对论)测量单独使用或与I-AC(相对论)数据相结合的值。(C)2004年,美国光电仪器工程师学会。
Frequency-domain photon migration measurements across the surface of a tissue-mimicking, semi-infinite phantom are acquired via an intensified charge-coupled device (ICCD) detection system and used in conjunction with the diffusion approximation to determine the optical properties. The absorption and reduced scattering coefficients are determined least accurately when relative measurements of I-dc(rel) age light intensity are employed either alone or in a combination with relative modulation amplitude data I-ac(rel) and/or relative phase shift data theta(rel). The absorption and reduced scattering coefficients are found accurate to within 15 and 11%, respectively, of the values obtained from standard single-pixel measurements when theta(rel) measurements are employed alone or in combination with I-ac(rel) data. (C) 2004 Society of Photo-Optical Instrumentation Engineers.