Genetic characterization and pathogenicity of a reassortant Eurasian avian-like H1N1 swine influenza virus containing an internal gene cassette from 2009 pandemic H1N1 virus
Genetic characterization and pathogenicity of a reassortant Eurasian avian-like H1N1 swine influenza virus containing an internal gene cassette from 2009 pandemic H1N1 virus
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DOI:
10.1016/j.virs.2022.04.009
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发表时间:
2022
期刊:
影响因子:
--
通讯作者:
Hai Yu
中科院分区:
文献类型:
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作者:
Shuaiyong Wang;Manzhu Wang;Lingxue Yu;Juan Wang;Jiecong Yan;Xinli Rong;Yanjun Zhou;Tongling Shan;Wu Tong;Guoxin Li;Hao Zheng;Guangzhi Tong;Hai Yu
• Identification of a reassortant EA H1N1 SIV (SD/18) which isolated from a pig farm in Shandong, north China. • Phylogenetic analysis showed that SD/18 virus containing a complete internal gene cassette from pdm/09 virus. • The results of pathogenicity in mice showed that the mortality rate of SD/18 virus in mice could reach 100%.