Fatal asthma or anaphylaxis?

Fatal asthma or anaphylaxis?
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DOI:
10.1136/emj.19.5.415
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发表时间:
2002-09-01
影响因子:
3.1
通讯作者:
Browne, GJ
Browne, GJ
中科院分区:
医学3区
文献类型:
--
作者:
Rainbow, J;Browne, GJ

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速发过敏反应的发生率报告不足。患有哮喘的儿童经常是特应性的,容易发生过敏反应。家长和临床医生可能将快速发作的喘息归因于急性重度哮喘,而不是认识到过敏性事件。报告了两例致死性过敏反应病例,最初诊断为急性重度哮喘,对支气管扩张剂治疗反应不佳。“急性窒息性哮喘”的幸存者应筛查对引起过敏反应的常见过敏原的反应。即使未发现诱发因素,急性窒息性哮喘发作后存活的儿童的哮喘管理计划除了常规的支气管扩张剂外,还应包括肌内注射肾上腺素(肾上腺素)。
The incidence of anaphylaxis is under-reported. Children with asthma are frequently atopic and prone to allergic reactions. Parents and clinicians may attribute wheeze of rapid onset to acute severe asthma, rather than recognising an anaphylactic event. Two cases of fatal anaphylaxis are reported who were initially diagnosed as acute severe asthma, and responded poorly to bronchodilator treatment. Survivors of "acute asphyxic asthma" should be screened for reactions to common allergens that provoke anaphylactic reactions. Even if no provoking factor is identified, the asthma management plan of children who survive an episode of acute asphyxic asthma should include intramuscular adrenaline (epinephrine) in addition to conventional bronchodilators.