Tracking the Spatiotemporal Neural Dynamics of Real-world Object Size and Animacy in the Human Brain
Tracking the Spatiotemporal Neural Dynamics of Real-world Object Size and Animacy in the Human Brain
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DOI：
10.1162/jocn_a_01290
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发表时间：
2018-11-01
影响因子：
3.2
通讯作者：
Oliva, Aude
中科院分区：
文献类型：
--
作者：
Khaligh-Razavi, Seyed-Mahdi;Cichy, Radoslaw Martin;Oliva, Aude
动画和真实世界的大小是描述任何物体的属性，从而为我们对视觉世界的感知带来基本秩序。在这里，我们研究了人类大脑是如何处理现实世界的大小和动画的。为此，我们将表征相似性应用于fMRI和MEG数据，分别获得具有高空间和时间分辨率的大脑活动视图。fMRI数据分析显示，从枕部到腹侧和内侧颞叶皮层的皮质区域分布和部分重叠，代表了动物和现实世界的大小。在这一组中，海马旁皮层作为比大多数其他区域更能代表活力和大小的区域脱颖而出。对详细表征格式的进一步分析揭示了涉及处理动画的区域之间的差异。对脑磁图数据的分析显示，动画和现实世界尺寸处理在150毫秒左右开始重叠时间动态，并提供了现实世界物体尺寸处理的第一个神经磁特征。最后，为了研究尺寸和动画处理同时在空间和时间上的神经动力学，我们将MEG和fMRI结合起来，并通过表征相似性对MEG和fMRI融合进行了新的扩展。这一分析揭示了部分重叠和分布的时空动态，海马旁皮层被挑出来作为一个区域，它持续地代表着大小和活力，而其他区域则没有。此外，该分析强调了早期视觉皮层在表征现实世界尺寸方面的作用。对照分析表明，处理动画和大小的神经动力学与处理低级视觉特征的神经动力学不同。总之，我们的研究结果提供了人类大脑中动画和尺寸处理的详细时空视图。
Animacy and real-world size are properties that describe any object and thus bring basic order into our perception of the visual world. Here, we investigated how the human brain processes real-world size and animacy. For this, we applied representational similarity to fMRI and MEG data to yield a view of brain activity with high spatial and temporal resolutions, respectively. Analysis of fMRI data revealed that a distributed and partly overlapping set of cortical regions extending from occipital to ventral and medial temporal cortex represented animacy and real-world size. Within this set, parahippocampal cortex stood out as the region representing animacy and size stronger than most other regions. Further analysis of the detailed representational format revealed differences among regions involved in processing animacy. Analysis of MEG data revealed overlapping temporal dynamics of animacy and real-world size processing starting at around 150 msec and provided the first neuromagnetic signature of real-world object size processing. Finally, to investigate the neural dynamics of size and animacy processing simultaneously in space and time, we combined MEG and fMRI with a novel extension of MEG-fMRI fusion by representational similarity. This analysis revealed partly overlapping and distributed spatiotemporal dynamics, with parahippocampal cortex singled out as a region that represented size and animacy persistently when other regions did not. Furthermore, the analysis highlighted the role of early visual cortex in representing real-world size. A control analysis revealed that the neural dynamics of processing animacy and size were distinct from the neural dynamics of processing low-level visual features. Together, our results provide a detailed spatiotemporal view of animacy and size processing in the human brain.