Least microtransfusion from mother to fetus in elective cesarean delivery

Least microtransfusion from mother to fetus in elective cesarean delivery
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DOI:
10.1016/0029-7844(95)00385-1
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发表时间:
1996-02-01
影响因子:
7.2
通讯作者:
Chen, DS
Chen, DS
中科院分区:
医学2区
文献类型:
--
作者:
Lin, HH;Kao, JH;Chen, DS

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目的:通过检测B型肝炎表面抗原(HBsAg)和胎盘碱性磷酸酶(AKP),探讨不同分娩方式下母胎微量输血的变异性。分娩方式包括选择性剖宫产16例,自然阴道分娩56例,真空或产钳分娩12例,临产后急诊剖宫产13例。我们测量了HBsAg和胎盘碱性磷酸酶水平在97对产妇和胎儿的血液样本收集在deliver.Results:平均产妇胎盘碱性磷酸酶水平没有显着差异,这四组。选择性剖宫产组脐带胎盘碱性磷酸酶水平最低(P <0.05)。该组所有脐带血清样本HBsAg均为阴性,而自然阴道组、真空或产钳组和紧急剖宫产组分别为38/56、8/12和7/13(P < .05)。结论:选择性剖腹产组的母胎微量输血水平最低,如最低脐带胎盘碱性磷酸酶和HBsAg水平所示。这些观察结果可能对减少血液传播病毒的围产期传播有影响。
Objective: To examine the variability of maternal-fetal microtransfusion in different modes of delivery, as measured by hepatitis B surface antigen (HBsAg) and placental alkaline phosphatase.Methods: We recruited 97 HBsAg-positive pregnant women. The mode of delivery included elective cesarean in 16, normal spontaneous vaginal delivery in 56, vacuum or forceps delivery in 12, and emergency cesarean after labor in 13. We measured HBsAg and placental alkaline phosphatase levels in 97 pairs of maternal and fetal blood samples collected at delivery.Results: The mean maternal placental alkaline phosphatase levels did not differ among these four groups. The mean cord placental alkaline phosphatase level of the elective cesarean group was the lowest (P < .05). All samples of cord sera for this group were negative for HBsAg, compared with 38 of 56, eight of 12, and seven of 13 in the spontaneous vaginal, vacuum or forceps, and emergency cesarean groups, respectively (P < .05).Conclusion: The level of mother-to-fetus microtransfusion was least in the elective cesarean group, as revealed by both the lowest cord placental alkaline phosphatase and HBsAg levels. These observations may have implications for reducing perinatal transmission of blood-borne viruses.