Likelihood of developing an alcohol and-cannabis use-disorder during youth: Association with recent use and age

Likelihood of developing an alcohol and-cannabis use-disorder during youth: Association with recent use and age
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DOI:
10.1016/j.drugalcdep.2007.08.005
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发表时间:
2008-01-01
影响因子:
4.2
通讯作者:
Lee, Chih-Yuan S.
Lee, Chih-Yuan S.
中科院分区:
医学2区
文献类型:
--
作者:
Winters, Ken C.;Lee, Chih-Yuan S.

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目的:我们通过调查最近开始的酒精和大麻使用在青春期和青年期的每个实际年龄赋予发展物质使用障碍的风险,扩展了关于早发性药物使用与发展物质使用障碍(SUD)的估计风险之间的关联的文献设计:使用2003年全国药物使用和健康调查的数据[药物滥用心理健康服务管理局(SAMHSA),2004年]。2003年全国药物使用与健康调查结果概述。应用研究办公室,NSDUH系列H-24,DHHS出版号SMA-04-3963,Rockville,MD],我们计算了最近发生酒精和大麻使用障碍的单独风险指数,(前2年)酒精和大麻使用者,分别在每个年龄从12岁到21岁,并比较估计的风险,最近发病的用户之间的受访者年龄22- 26。结果表明,青少年时期与高风险状态密切相关。与22-26岁的近期发病饮酒者中的AUD估计风险相比,14岁、16岁、17岁和18岁的年轻人中最近一年酒精使用障碍(AUD)的比值比(OR)显著升高(OR范围= 2.0-2.1)。对于大麻,我们获得显着升高的OR的大麻使用障碍(CUD)在每个十几岁(12-18岁; OR的范围= 3.9-7.2),相比,年龄较大的最近发病的用户(22-26岁)。结论:这些数据提供了进一步的流行病学支持,青春期是一个特别脆弱的时期,发展一个SUD。(c)2007爱思唯尔爱尔兰有限公司保留所有权利。
Aim: We extend the literature on the association of early onset of drug use and estimated risk for developing a substance use disorder (SUD) by investigating the risk that recent onset of alcohol and cannabis use confers for developing a substance use disorder at each chronological age of adolescence and young adulthood (12-21-years-old).Design: Using 2003 data from the National Survey on Drug Use and Health [Substance Abuse Mental Health Service Administration (SAMHSA), 2004. Overview of Findings from the 2003 National Survey on Drug Use and Health. Office of Applied Studies, NSDUH Series H-24, DHHS Publication No. SMA-04-3963, Rockville, MD], we computed separate risk indices for developing an alcohol and cannabis use disorder for recent (prior 2 years) alcohol and cannabis users, respectively, at each age from 12 to 21 years of age, and compared estimated risk to recent onsets users among respondents aged 22-26.Findings: The results indicated that the teenage years were strongly linked to an elevated risk status. The odds ratio (OR) of having a prior year alcohol use disorder (AUD) among recent onset alcohol users was significantly elevated for youth at ages 14, 16, 17 and 18 (range of ORs = 2.0-2.1) compared to the estimated risk for AUD among recent onset users aged 22-26. For cannabis, we obtained significantly elevated ORs for a cannabis use disorder (CUD) at each of teenage years (ages 12-18; range of ORs = 3.9-7.2), when compared to older recent onset users (aged 22-26).Conclusions: These data provide further epidemiological support that adolescence is a particularly vulnerable period for developing a SUD. (c) 2007 Elsevier Ireland Ltd. All rights reserved.