Simple and associative recognition memory in the hippocampal region.

Simple and associative recognition memory in the hippocampal region.
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海马区的简单联想识别记忆。

DOI:
10.1101/lm.40701
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发表时间:
2001
期刊:
Learning & memory (Cold Spring Harbor, N.Y.)
影响因子:
--
通讯作者:
Squire,LR
Squire,LR
中科院分区:
--
文献类型:
--
作者:
Stark,CE;Squire,LR

文献摘要

被引文献

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虽然海马区参与了陈述性记忆的形成,但其参与的确切性质尚不清楚。一种观点认为,海马区只参与需要形成或使用联想的任务。根据这一观点,海马区并不参与传统的识别记忆测试。另一种观点是,海马区结合并扩展了海马旁回结构进行的处理,并且它参与所有形式的陈述性记忆,包括识别记忆。使用事件相关功能磁共振成像(fMRI),我们观察海马活动在传统和联想识别记忆任务。关键的是,海马区在联想识别任务中并不比在传统识别任务中更活跃。
Although it is well established that the hippocampal region is involved in the formation of declarative memory, the exact nature of its involvement is unclear. One view is that the hippocampal region is involved only in tasks that require the formation or use of associations. According to this view, the hippocampal region is not involved in traditional tests of recognition memory. An alternative view is that the hippocampal region combines and extends the processing carried out by structures in the parahippocampal gyrus and that it is involved in all forms of declarative memory, including recognition memory. Using event-related functional magnetic resonance imaging (fMRI), we observed hippocampal activity during both traditional and associative recognition memory tasks. Critically, the hippocampal region was no more active in the associative recognition task than in the traditional recognition task.