Utility of point-of-care vs reference laboratory testing for the evaluation of glucose levels.

Utility of point-of-care vs reference laboratory testing for the evaluation of glucose levels.
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即时护理与参考实验室测试在评估血糖水平方面的效用。

DOI:
10.1111/dme.13922
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发表时间:
2019
期刊:
Diabetic medicine : a journal of the British Diabetic Association
影响因子:
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通讯作者:
Joshipura,K
Joshipura,K
中科院分区:
--
文献类型:
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作者:
Andriankaja,OM;Muñoz-Torres,FJ;Vergara,JL;Pérez,CM;Joshipura,K

文献摘要

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AimsTo评估点的护理和实验室参考葡萄糖值之间的协议水平在定义hyperemic status.MethodsWe分析了1292超重/肥胖,非制度化的参与者,年龄在40-65岁,在圣胡安超重成人纵向研究。使用床旁Bayer Contour血糖仪和Vitros System 250仪器(实验室)测定空腹静脉血糖。美国糖尿病协会阈值被用来分类参与者正常血糖(< 5.6 mmol/l),糖尿病前期(5.6至6.9 mmol/l),或糖尿病组(≥ 7 mmol/l)。结果Bland-Altman图分析显示,斜率为0.04(P=0.002)的平均差异和两种方法的平均值之间的回归。正常血糖组(β=-0.57,P <$0.001)和糖尿病前期组(β=-0.75,P <$0.001)的斜率与0有显著性差异,但糖尿病组之间无显著性差异(β=-0.02,P = 0.68)。当糖尿病前期和糖尿病组合并为一组时,斜率为0.01,使用两种方法的葡萄糖值保持相似(P=0.76)。结论床旁血糖测量可能有助于筛查糖尿病患者,并评估可抽血的糖尿病患者的血糖,但实验室检查不可用或不及时。
AimsTo assess the level of agreement between point‐of‐care and laboratory reference glucose values in defining glycaemic status.MethodsWe analysed 1292 overweight/obese, non‐institutionalized participants, aged 40–65 years, in the San Juan Overweight Adults Longitudinal Study. Fasting venous blood glucose was determined using a point‐of‐care Bayer Contour Blood Glucose Meter and by Vitros System 250 instrument (laboratory). American Diabetes Association thresholds were used to classify participants into normoglycaemia (< 5.6 mmol/l), prediabetes (5.6 to 6.9 mmol/l), or diabetes groups (≥ 7 mmol/l).ResultsBland–Altman plot analysis showed a slope of 0.04 (P=0.002) for the regression between the mean difference and the average of the two methods. The slopes were significantly different from zero among people with normoglycaemia (β=–0.57,P<0.001), and prediabetes (β=–0.75,P<0.001) but not among people with diabetes (β=–0.02,P=0.68). When the prediabetes and diabetes groups were merged into one group, the slope was 0.01, and the glucose values remained similar using the two methods (P=0.76).ConclusionPoint‐of‐care blood glucose measurement may be useful to screen people with diabetes, and to assess glucose among individuals with diabetes where blood can be drawn, but laboratory tests are unavailable or untimely.