Action currents in single afferent nerve fibres elicited by stimulation of the skin of the toad and the cat

Action currents in single afferent nerve fibres elicited by stimulation of the skin of the toad and the cat
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刺激蟾蜍和猫的皮肤引起的单传入神经纤维的动作电流

DOI:
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发表时间:
1952
期刊:
Journal of Physiology
影响因子:
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通讯作者:
I. Tasaki
I. Tasaki
中科院分区:
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文献类型:
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作者:
J. Maruhashi;K. Mizuguchi;I. Tasaki

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结论.利用这种技术,很容易记录单个神经纤维中的感觉放电,这些神经纤维产生了压倒性的大动作电位,或者在对感觉刺激具有特别低的阈值的纤维中。然而,探索神经末梢的行为是极其困难的,因为这些纤维中的放电可能完全被其他主要纤维中的放电所掩盖,这些神经末梢在刺激时产生有限数量的小动作电位。该技术的这一缺陷和其他缺陷无疑可以通过使用所需尺寸的单个隔离光纤进行实验来规避。自1942年以来,一。us(LT.),与几位同事合作,不时更换,致力于用单纤维技术探索各种感觉神经末梢的生理特性。通过我们现在使用的实验装置,有可能在单个神经纤维中观察传入冲动,无论是有髓鞘的还是无髓鞘的。
conclusions. With this technique it is easy to record sensory discharges in single nerve fibres which develop overwhelmingly large action potentials or in fibres with especially low threshold for sensory stimuli. It is, however, extremely difficult to explore the behaviour of nerve endings which on stimulation give rise to a limited number of small action potentials, because the discharges in these fibres may be completely masked by those in other predominant fibres. This and other defects of the technique can undoubtedly be circumvented by using a single isolated fibre of the desired size for the experiments. Since 1942 one of. us (LT.), in collaboration with several co-workers who changed from time to time, has devoted much effort to exploring the physiological properties of various sensory nerve endings with the single fibre technique. By means of the experimental set-up we are using now, it is possible to observe afferent impulses in a single nerve fibre, either myelinated