LYME-DISEASE - A TICK-BORNE SPIROCHETOSIS
LYME-DISEASE - A TICK-BORNE SPIROCHETOSIS
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DOI：
10.1126/science.7043737
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发表时间：
1982-01-01
期刊：
影响因子：
56.9
通讯作者：
DAVIS, JP
中科院分区：
文献类型：
--
作者：
BURGDORFER, W;BARBOUR, AG;DAVIS, JP
在莱姆病的病原蜱媒成年大伊蚊中发现并分离出一种密螺旋体样螺旋体。与螺旋体有因果关系的可能是受感染的蜱虫以新西兰白兔为食后10-12周出现的长期皮肤病变。间接免疫荧光法显示莱姆病患者血清样品中含有该药物的抗体。因此，新发现的螺旋体可能与莱姆病的病因有关。
A Treponema-like spirochete was detected in and isolated from an adult Ixodes dammini, the incriminated tick vector of Lyme disease. Causally related to the spirochetes may be long-lastig cutaneous lesions that appeared on New Zealand White rabbits 10-12 wk after infected ticks fed on them. Samples of serum from patients with Lyme disease were shown by indirect immunofluorescence to contain antibodies to this agent. Thus, the newly discovered spirochete may be involved in the etiology of Lyme disease.