PERCUTANEOUS LARGE-CORE BREAST BIOPSY - A MULTIINSTITUTIONAL STUDY

PERCUTANEOUS LARGE-CORE BREAST BIOPSY - A MULTIINSTITUTIONAL STUDY
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DOI:
10.1148/radiology.193.2.7972743
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发表时间:
1994-11-01
期刊:
影响因子:
19.7
通讯作者:
WYNN, RT
WYNN, RT
中科院分区:
医学1区
文献类型:
--
作者:
PARKER, SH;BURBANK, F;WYNN, RT

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目的:评估自动化大型核心活检的可靠性和可重复性。材料和方法:由 20 家机构组成的联盟以标准化方式报告了其核心乳腺活检数据。所有活检均使用配有 14 号针头的“长距离”(2.3 厘米)自动核心活检装置进行。针引导是通过专用立体定位设备(患者处于俯卧位)或高频电子聚焦超声设备来完成的。 结果:收集了 6,152 个病变的数据。对 3,765 个病灶进行了临床或手术随访;其中 1,363 个病灶随后被手术切除,核心组织学研究显示 910 个病灶为癌症,173 个病灶为乳腺上皮内瘤变,280 个病灶为良性疾病。在这 280 个病变中,有 15 个假阴性核心活检。 结论:数据表明,经皮大核心乳腺活检是手术活检的一种可重复且可靠的替代方案。
PURPOSE: To assess the reliability and reproducibility of automated large-coreMATERIALS AND METHODS: A consortium of 20 institutions reported, in a standardized fashion, their core breast biopsy data. All biopsies were performed with ''long-throw'' (2.3-cm) automated core biopsy devices fitted with 14-gauge needles. Needle guidance was accomplished by means of either a dedicated, stereotaxic device, in which the patient lies in the prone position, or high-frequency electronically focused ultrasound equipment.RESULTS: The data in 6,152 lesions were gathered. Clinical or surgical follow-up was available in 3,765 lesions; 1,363 of these lesions were subsequently surgically excised, and the core histologic study showed cancer in 910 lesions, mammary intraepithelial neoplasia in 173 lesions, and benign disease in 280 lesions. In these 280 lesions, there were 15 false-negative core biopsies.CONCLUSION: The data show that percutaneous large-core breast biopsy is a reproducible and reliable alternative to surgical biopsy.