Diurnal variations in luminal and stromal areas of choroid in normal eyes.
Diurnal variations in luminal and stromal areas of choroid in normal eyes.
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DOI：
10.1136/bjophthalmol-2016-308594
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发表时间：
2017-03
期刊：
影响因子：
--
通讯作者：
Sakamoto T
中科院分区：
文献类型：
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作者：
Kinoshita T;Mitamura Y;Shinomiya K;Egawa M;Iwata A;Fujihara A;Ogushi Y;Semba K;Akaiwa K;Uchino E;Sonoda S;Sakamoto T
目的：测定正常人眼脉络膜腔内和基质区的昼夜变化。这是一项对38名正常人的38只眼进行的前瞻性观察研究。在6：00~21：00 小时内每隔3 小时记录血压、心率、眼压和增强深度成像光学相干断层扫描(EDI-OCT)图像。将中心凹下脉络膜的水平EDI-OCT图像转换为二值化图像。测定中心脉络膜厚度、脉络膜总截面积、管腔面积、管腔间质面积及管腔面积与脉络膜总面积的比值(L/C)。脉络膜中央CT、脉络膜总面积、管腔面积和L/C比值有明显的日变化，6：00 时最大，15：00 时最小(P<；0.001，脉络膜总面积p=0.011，管腔面积p<；0.001，L/C比值p=0.014)。基质面积无明显变化(p=0.216)。中心脉络膜厚度的波动范围与管腔面积和脉络膜总面积的波动范围显著相关(p<；0.001)。然而，中央CT的波动范围与间质区域的波动范围之间没有显著相关性(p=0.095)。脉络膜参数与全身参数之间无统计学关系。管腔面积的变化很可能是CCT和中心凹下脉络膜区域昼夜变化的原因。UMIN000019060，预结果。
To determine the diurnal variations of the luminal and stromal areas of the choroid in normal eyes. This was a prospective observational study of 38 eyes of 38 normal subjects. The blood pressure, heart rate, intraocular pressure and enhanced depth imaging optical coherence tomographic (EDI-OCT) images were recorded every 3 hours between 6:00 and 21:00 hours. The horizontal EDI-OCT images of the subfoveal choroid were converted to binary images. The central choroidal thickness (CCT), total cross-sectional choroidal area, the luminal areas, stromal areas and the ratio of luminal area to total choroidal area (L/C ratio) were determined. There were significant diurnal variations in the CCT, total choroidal area, luminal area and L/C ratio with the maximum values at 6:00 hours and the minimum values at 15:00 hours (p<0.001 for the CCT, p=0.011 for the total choroidal area, p<0.001 for the luminal area and p=0.014 for the L/C ratio). There was no significant variation in the stromal area (p=0.216). The range of fluctuation in the CCT was significantly correlated with that in the luminal area and the total choroidal area (p<0.001). However, there was no significant correlation between the fluctuation range in the CCT and that in the stromal area (p=0.095). There was no statistical relationship between the systemic parameters and the choroidal parameters. The changes in the luminal area are most likely responsible for the diurnal change in the CCT and subfoveal choroidal area. UMIN000019060, Pre-results.