Programmed Cell Death: Central Player in Fungal Infections.
Programmed Cell Death: Central Player in Fungal Infections.
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程序性细胞死亡:真菌感染的中心角色。
DOI:
10.1016/j.tcb.2020.11.005
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发表时间:
2021-03
影响因子:
19
通讯作者:
Richardson JP
中科院分区:
文献类型:
--
作者:
Camilli G;Blagojevic M;Naglik JR;Richardson JP
Fungal diseases contribute significantly to morbidity and mortality in humans. Although recent research has improved our understanding of the complex and dynamic interplay that occurs between pathogenic fungi and the human host, much remains to be elucidated concerning the molecular mechanisms that drive fungal pathogenicity and host responses to fungal infections. In recent times, there has been a significant increase in studies investigating the immunological functions of microbial-induced host cell death. In addition, pathogens use many strategies to manipulate host cell death pathways to facilitate their survival and dissemination. This review will focus on the mechanisms of host programmed cell death that occur during opportunistic fungal infections and explore how cell death pathways may affect immunity towards pathogenic fungi.
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发表时间:
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通讯作者:
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DOI:
10.1038/s41577-019-0240-6
发表时间:
2020-04
期刊:
Nature reviews. Immunology
影响因子:
--
作者:
Doran AC;Yurdagul A Jr;Tabas I
通讯作者:
Tabas I