Models of data and theoretical hypotheses: a case-study in classical genetics
Models of data and theoretical hypotheses: a case-study in classical genetics
复制标题
数据模型和理论假设:经典遗传学的案例研究
DOI:
10.1007/s11229-012-0147-2
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发表时间:
2012
期刊:
影响因子:
1.5
通讯作者:
Vorms M
中科院分区:
文献类型:
--
作者:
Vorms M
Linkage (or genetic) maps are graphs, which are intended to represent the linear ordering of genes on the chromosomes. They are constructed on the basis of statistical data concerning the transmission of genes. The invention of this technique in 1913 was driven by Morgan’s group’s adoption of a set of hypotheses concerning the physical mechanism of heredity. These hypotheses were themselves grounded in Morgan’s defense of the chromosome theory of heredity, according to which chromosomes are the physical basis of genes. In this paper, I analyze the 1919 debate between William Castle and Morgan’s group, about the construction of genetic maps. The official issue of the debate concerns the arrangement of genes on chromosomes. However, the disputants tend to carry out the discussions about how one should model the data in order to draw predictions concerning the transmission of genes; the debate does not bear on the data themselves, nor does it focus on the hypotheses explaining these data. The main criteria that are appealed to by the protagonists are simplicity and predictive efficacy. However, I show that both parties’ assessments of the simplicity and predictive efficacy of different ways of modeling the data themselves depend on background theoretical positions. I aim at clarifying how preference for a given model and theoretical commitments articulate.
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DOI:
--
发表时间:
--
影响因子:
11.1
作者:
A. Sturtevant;C. Bridges;T. Morgan
通讯作者:
T. Morgan
DOI:
10.2307/1535510
发表时间:
1902
期刊:
The Biological Bulletin
影响因子:
--
作者:
W. S. Sutton
通讯作者:
W. S. Sutton
DOI:
--
发表时间:
1971
期刊:
Centaurus; international magazine of the history of science and medicine
影响因子:
--
作者:
W. Coleman
通讯作者:
W. Coleman
DOI:
--
发表时间:
--
期刊:
影响因子:
--
作者:
C. Chant
通讯作者:
C. Chant
影响因子:
56.9
作者:
C. R. Mann
通讯作者:
C. R. Mann