Association between sleep disturbance in Alzheimer's disease patients and burden on and health status of their caregivers
Association between sleep disturbance in Alzheimer's disease patients and burden on and health status of their caregivers
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DOI：
10.1007/s00415-019-09286-0
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发表时间：
2019-06-01
影响因子：
6
通讯作者：
Tokita, Shigeru
中科院分区：
文献类型：
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作者：
Okuda, Shoki;Tetsuka, Jumpei;Tokita, Shigeru
阿尔茨海默病（AD）患者的睡眠障碍不仅会对患者自身产生负面影响，也会对其照顾者的身心健康产生负面影响。缺乏对这些问题的详细分析。目的探讨日本老年痴呆症患者睡眠障碍与照护者负担及健康状况的关系。方法对日本伴有失眠症状的AD患者的护理人员进行了一项基于网络的横断面问卷调查。收集患者的人口学数据和睡眠障碍量表（SDI）评分、照顾者负担（burden Index of caregiers -11 [BIC-11]）和健康状况，包括匹兹堡睡眠质量指数、患者健康问卷-9和12项简短健康调查v2。采用多变量分析来检验照顾者负担和健康状况与阿尔茨海默病患者睡眠障碍之间的关系。结果本研究共调查了496名伴有失眠症状的AD患者的护理人员。我们发现，随着SDI评分的增加，BIC-11总分也会增加，即使在调整了混杂因素后，也显示出显著的正相关。我们还发现阿尔茨海默病患者的睡眠障碍与照顾者的健康（睡眠质量、抑郁和身体/精神生活质量）之间存在关联。结论阿尔茨海默病患者睡眠障碍与照顾者负担增加和健康状况恶化有关。我们的研究结果强调了睡眠管理对阿尔茨海默病患者的重要性。
BackgroundSleep disturbance in Alzheimer's disease (AD) patients may have a negative impact not only on patients themselves but also on the physical and mental health of their caregivers. Detailed analysis of these issues is lacking.ObjectiveThis study investigated the association between sleep disturbance in AD patients and the burden on, and health status of, their caregivers in Japan.MethodsWe conducted a cross-sectional web-based questionnaire survey among caregivers of AD patients with insomnia symptoms in Japan. Demographic data and Sleep Disorders Inventory (SDI) scores for patients, caregiver burden (Burden Index of Caregivers-11 [BIC-11]) and health status, including Pittsburgh Sleep Quality Index, Patient Health Questionnaire-9, and 12-Item Short Form Health Survey v2, were collected. Multivariate analysis was used to examine the association between the burden and health status of caregivers and sleep disturbance in their care recipients with AD.ResultsA total of 496 caregivers of AD patients with insomnia symptoms were examined in this study. We found that the BIC-11 total score increased as the SDI score increased, indicating a significant positive association, even after adjusting for confounding factors. We also found an association between sleep disturbances of AD patients and health of caregivers (sleep quality, depression, and physical/mental quality of life).ConclusionThis study demonstrated that sleep disturbance in AD patients was associated with an increased burden and poorer health status of caregivers. Our findings highlight the importance of sleep management in AD patients.