MITOCHONDRIAL HEAT-SHOCK PROTEIN HSP60 IS ESSENTIAL FOR ASSEMBLY OF PROTEINS IMPORTED INTO YEAST MITOCHONDRIA
MITOCHONDRIAL HEAT-SHOCK PROTEIN HSP60 IS ESSENTIAL FOR ASSEMBLY OF PROTEINS IMPORTED INTO YEAST MITOCHONDRIA
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DOI：
10.1038/337620a0
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发表时间：
1989-02-16
期刊：
影响因子：
64.8
通讯作者：
HORWICH, AL
中科院分区：
文献类型：
--
作者：
CHENG, MY;HARTL, FU;HORWICH, AL
核编码的线粒体热休克蛋白Hsp60需要组装成输入到线粒体基质中的蛋白质的寡聚复合体。HSP60是蛋白质伴侣蛋白家族的一员，包括大肠杆菌GroEL蛋白和叶绿体Rubisco亚基结合蛋白。
A nuclear encoded mitochondrial heat-shock protein hsp60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. hsp60 is a member of the 'chaperonin' class of protein factors, which include the Escherichia coli groEL protein and the Rubisco subunit-binding protein of chloroplasts.