[The current antimicrobial resistance situation in Swiss veterinary medicine].
[The current antimicrobial resistance situation in Swiss veterinary medicine].
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DOI：
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发表时间：
2001-10
影响因子：
0.7
通讯作者：
A. Wissing;J. Nicolet;P. Boerlin
中科院分区：
文献类型：
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作者：
A. Wissing;J. Nicolet;P. Boerlin
从1999年5月至2000年2月，与8个瑞士实验室合作，收集了来自动物的重要细菌病原体的抗菌药物敏感性数据（n = 1501）和细菌分离株（n = 258）。使用这些数据，可以评估以下细菌种属的抗菌剂耐药性情况：大肠埃希菌、沙门氏菌、副猪嗜血杆菌、胸膜肺炎放线杆菌、多杀性巴氏杆菌、溶血性曼氏杆菌、支气管败血波氏杆菌、空肠弯曲杆菌、铜绿假单胞菌、金黄色葡萄球菌、中间葡萄球菌、链球菌和肠球菌。不同动物种间的抗性分布差异可在E.大肠杆菌和沙门氏菌。一些电阻频率数据进行了比较，在1980年获得的。几种抗生素的耐药频率显着增加。这尤其包括大肠杆菌对氨苄青霉素、庆大霉素和复方新诺明耐药性的增加。杆菌氨苄西林、链霉素、磺胺类药物和萘啶酸的saltrin也出现类似增加。犬源葡萄球菌（S. intermedius和S.金黄色葡萄球菌）对青霉素、新霉素、磺胺类、复方新诺明和红霉素的耐药性也明显增加。最后，与国外数据的比较表明，瑞士的抗生素耐药性状况相对有利。
Antimicrobial susceptibility data (n = 1501) and bacterial isolates (n = 258) of important bacterial pathogens from animals were collected in collaboration with eight Swiss laboratories from May 1999 to February 2000. Using these data, the antimicrobial resistance situation could be assessed for the following bacterial species: Escherichia coli, Salmonella, Haemophilus parasuis, Actinobacillus pleuropneumoniae, Pasteurella multocida, Mannheimia haemolytica, Bordetella bronchiseptica, Campylobacter jejuni, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus intermedius, Streptococci, and enterococci. Differences in the distribution of resistance between animal species could be evidenced in E. coli and salmonella. Some resistance frequency data were compared with those obtained in 1980. A significant increase of resistance frequency was observed for several antibiotics. This includes in particular an increase of ampicillin, gentamicin, and cotrimoxazole resistance in E. coli. A similar increase was observed in salmonella for ampicillin, streptomycin, sulfonamides, and nalidixic acid. Staphylococci from dogs (S. intermedius and S. aureus) also presented a clear increase of resistance for penicillin, neomycin, sulfonamides, cotrimoxazole, and erythromycin. Finally, a comparison with data from abroad shows that the antibiotic resistance situation in Switzerland is relatively favorable.