The validity of the Dutch K10 and extended K10 screening scales for depressive and anxiety disorders
The validity of the Dutch K10 and extended K10 screening scales for depressive and anxiety disorders
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DOI：
10.1016/j.psychres.2009.01.012
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发表时间：
2010-03-30
影响因子：
11.3
通讯作者：
Penninx, Brenda
中科院分区：
文献类型：
--
作者：
Donker, Tara;Comijs, Hannie;Penninx, Brenda
本研究的目的是验证荷兰版 Kessler-10 (K10) 以及扩展版 (EK10) 在初级保健中筛查抑郁症和焦虑症的作用。数据来自荷兰抑郁和焦虑研究 (NESDA) 的 1607 名参与者（18 至 65 岁，68.8% 女性），从 65 名全科医生中招募。参与者完成了 K10，并补充了五个针对核心焦虑症状的附加问题，并通过 WHO 综合国际诊断访谈（CID！终身版本 2.1）进行评估，以评估 DSM-IV 疾病（重度抑郁症、心境恶劣、广泛性焦虑症、社交恐惧症、恐慌症、广场恐惧症）。荷兰 K10 的可靠性（Cronbach's a）为 0.94。根据受试者操作特征 (ROC) 分析，任何抑郁症和/或焦虑症的 K10 曲线下面积 (AUC) 均为 0.87。 EK10 上的扩展问题显着提高了焦虑症的检测率。以 20 为截止点，K10 对于任何抑郁症和/或焦虑症的敏感性为 0.80，特异性为 0.81。对于 EK10，20 分的分界点和/或对附加问题至少有一个肯定回答为检测任何抑郁症和/或焦虑症提供了 0.90 的敏感性和 0.75 的特异性。荷兰版 K10 适用于初级保健中筛查抑郁症，而 EK10 则首选筛查抑郁症和焦虑症。 (C) 2009 Elsevier Ireland Ltd. 保留所有权利。
The aim of this study was to validate the Dutch version of the Kessler-10 (K10) as well as an extended version (EK10) in screening for depressive and anxiety disorders in primary care. Data are from 1607 participants (18 through 65 years, 68.8% female) of the Netherlands Study of Depression and Anxiety (NESDA), recruited from 65 general practitioners. Participants completed the K10, extended with five additional questions focusing on core anxiety symptoms, and were evaluated with the WHO Composite International Diagnostic Interview (CID! lifetime version 2.1) to assess DSM-IV disorders (major depressive disorder, dysthymia, generalized anxiety disorder, social phobia, panic disorder, agoraphobia). Reliability (Cronbach's a) of the Dutch K10 was 0.94. Based on Receiver Operating Characteristics (ROC) analysis, the area under the curve (AUC) for the K10 for any depressive and/or anxiety disorder was found to be 0.87. The extended questions on the EK10 significantly improved the detection of anxiety disorders in particular. With a cut-off point of 20, the K10 reached a sensitivity of 0.80 and a specificity of 0.81 for any depressive and/or anxiety disorder. For the EK10, a cut-off point of 20 and/or at least one positive answer on the additional questions provided a sensitivity of 0.90 and a specificity of 0.75 for detecting any depressive and/or anxiety disorder. The Dutch version of the K10 is appropriate for screening depressive disorders in primary care, while the EK10 is preferred in screening for both depressive and anxiety disorders. (C) 2009 Elsevier Ireland Ltd. All rights reserved.