Integrated multiplexed biosensors based on liquid core optical ring resonators and antiresonant reflecting optical waveguides

Integrated multiplexed biosensors based on liquid core optical ring resonators and antiresonant reflecting optical waveguides
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DOI:
10.1063/1.2387112
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发表时间:
2006-11-06
影响因子:
4
通讯作者:
Zhang, Junying
Zhang, Junying
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
White, Ian M.;Oveys, Hesam;Zhang, Junying

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作者演示了集成生物传感器,利用反谐振反射光波导(ARROW)激发回音壁模式的液芯光学环形谐振器(LCORR)传感器。由于这种架构是基于集成的,因此它非常健壮,非常适合传感器的密集多路复用。他们分析和实验表征的ARROW结构和LCORR之间的耦合,并表现出良好的耦合理论和实验结果之间的协议。多路复用能力的实验证明,通过激励多个环形谐振器沿着一个单一的LCORR使用的箭头阵列。此外,他们还展示了使用该LCORR-ARROW系统的牛血清白蛋白的无标记检测。
The authors demonstrate integrated biosensors utilizing antiresonant reflecting optical waveguides (ARROWs) to excite the whispering gallery modes of a liquid core optical ring resonator (LCORR) sensor. Because this architecture is based on integration, it is robust and well suited for dense multiplexing of sensors. They analytically and experimentally characterize the coupling between the ARROW structure and the LCORR and show good agreement between the coupling theory and experimental results. The multiplexing capability is experimentally demonstrated by exciting multiple ring resonators along a single LCORR using the ARROW array. Also, they show the label-free detection of bovine serum albumin with this LCORR-ARROW system.