Se-derivatized RNAs for X-ray crystallography.
Se-derivatized RNAs for X-ray crystallography.
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用于 X 射线晶体学的 Se 衍生化 RNA。
DOI：
10.1007/978-1-62703-113-4_16
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Huang,Zhen
中科院分区：
文献类型：
--
作者：
Lin,Lina;Huang,Zhen
Selenium derivatization of RNA is an important strategy for crystal structure determination and functional studies of noncoding RNAs and protein–RNA interactions. We describe here the synthesis of nucleoside 5′-(α-P-seleno)-triphosphate analogs (Se-NTPs) and their use in vitro transcription and purification of Se-derivatized RNA samples (phosphoroselenoate RNA, PSe-RNA).
