Burden of osteoporosis and fractures.
Burden of osteoporosis and fractures.
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DOI：
10.1007/s11914-003-0011-x
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发表时间：
2003-09-01
影响因子：
4.3
通讯作者：
Keen, Richard W
中科院分区：
文献类型：
--
作者：
Keen, Richard W
骨质疏松症目前影响着多达三分之一的女性和十二分之一的男性。1990年，全世界每年有160万例髋部骨折，预计到2050年这一数字将达到600万例。骨折数量的增加是由于人口中老年人数量的增加，生存率的提高，以及不明原因的年龄特异性骨折发生率的增加。骨质疏松性骨折及其相关发病率的上升将给未来的卫生保健资源带来沉重负担。在美国，骨质疏松症的治疗费用估计为170亿美元。这笔费用的大部分用于髋部骨折后的急性手术和医疗管理以及随后的康复。目前，用于治疗和预防骨质疏松症的费用很少。然而，有希望的是，对骨质疏松症对个人和卫生保健系统的负担的准确评估将使资源的目标能够解决这一日益严重的问题。随着越来越多的有效药物干预，这些药物针对那些未来骨折风险最大的患者至关重要。这将最终减轻未来几年骨质疏松症的负担。
Osteoporosis currently affects up to one in three women and one in 12 men. In 1990, there were 1.6 million hip fractures per annum worldwide and this number is estimated to reach 6 million by 2050. This increase in the number of fractures is due to an increase in the number of elderly people in the population, improved survival, and an increase in the age-specific fracture rates of unknown etiology. The rising number of osteoporotic fractures and their associated morbidity will place a heavy burden on future health care resources. In the United States, the cost for the management of osteoporosis has been estimated at $17 billion. The majority of this cost is spent on the acute surgical and medical management following hip fracture, and the subsequent rehabilitation. Currently, only minimal costs are utilized for treatment and prevention of osteoporosis. Hopefully, however, an accurate assessment of the burden of osteoporosis on the individual and the health care system will enable the targeting of resources to tackle this growing problem. With an increasing number of effective pharmaceutical interventions, it is critical that these agents are targeted to those at greatest risk for future fracture. This will ultimately reduce the burden of osteoporosis in future years.