First Impressions Matter: How Initial Worries Influence Adherence to the Dapivirine Vaginal Ring
First Impressions Matter: How Initial Worries Influence Adherence to the Dapivirine Vaginal Ring
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DOI：
10.1097/qai.0000000000002028
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发表时间：
2019-07-01
影响因子：
3.6
通讯作者：
Mhlanga, Felix
中科院分区：
文献类型：
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作者：
van der Straten, Ariane;Browne, Erica N.;Mhlanga, Felix
Background: In MTN-020/ASPIRE, a dapivirine vaginal ring effectiveness trial in sub-Saharan Africa, we assessed whether worries about ring use changed over time and were associated with adherence.Methods: Participants (N = 2585) were surveyed at baseline and follow-up about worries regarding daily ring use. First, they answered a question about general worries and then responded to 15 items covering specific worries. From a nested qualitative component (N = 214), we extracted themes related to ring worries and adherence. Seven months into the trial, aggregate adherence data were shared with study sites as part of an intervention that included counseling and social support. Nonadherence was defined as dapivirine plasma levels of
