Continuous enteral feeding: a major cause of pneumonia among ventilated intensive care unit patients.
Continuous enteral feeding: a major cause of pneumonia among ventilated intensive care unit patients.
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持续肠内喂养：通气重症监护病房患者肺炎的主要原因。
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
F. Bartlett
中科院分区：
文献类型：
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作者：
S. Jacobs;R. Chang;Bernie Lee;F. Bartlett
持续肠内营养在重症监护病房（ICU）中广泛应用。我们发现，在24例持续肠内营养超过3天的通气患者中，54%发生肺炎。这似乎只影响早晨（7：00 am）胃pH持续高的患者，13例患者中有12例（92%）发生肺炎。在11例患者中，在并发肺炎之前，病原体最初从胃、口咽和气管培养。这种效果与预防性使用抗酸剂或H2受体拮抗剂所发现的效果不同。该组患者的死亡率（46%）是Apache II疾病严重程度分类系统预测的预期死亡率的1.6倍。
Continuous enteral feeding is widely practiced in intensive care units (ICU). We found that pneumonia developed in 54% of 24 ventilated patients on continuous enteral feeding for more than 3 days. This appeared to affect only patients with a persistently high morning (7:00 am) gastric pH, with 12 of 13 (92%) patients developing pneumonia. In 11 patients the causative organisms were cultured initially from the stomach, oropharynx and trachea before pneumonia supervened. This effect was distinct from that found with the prophylactic use of antacids or H2-receptor antagonists. The mortality (46%) of this group of patients was 1.6 times greater than the expected mortality predicted by the Apache II Severity of Disease Classification System.
接受机械通气患者的肠内营养。
DOI：
10.1016/0002-9343(86)90623-6
发表时间：
1986
期刊：
The American journal of medicine
影响因子：
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作者：
Pingleton,SK;Hinthorn,DR;Liu,C
通讯作者：
Liu,C