Behavioral paradigms to evaluate PPAR modulation in animal models of brain injury.
Behavioral paradigms to evaluate PPAR modulation in animal models of brain injury.
复制标题
评估脑损伤动物模型中 PPAR 调节的行为范式。
DOI:
10.1007/978-1-62703-155-4_24
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发表时间:
2013
期刊:
影响因子:
--
通讯作者:
Robbins,MikeE
中科院分区:
文献类型:
--
作者:
Greene-Schloesser,Dana;Schnegg,CarolineI;Robbins,MikeE
The use of behavioral testing has become an invaluable tool for assessing the efficacy of therapeutics for a variety of disorders of the central nervous system. This chapter will describe in detail several behavioral paradigms to evaluate the efficacy of PPAR agonists to modulate cognitive impairments in rodent models. When used together as a battery these procedures allow for a global assessment of cognition. These tests are explained in detail below, and include: (1) Novel Object Recognition (NOR), (2) Morris Water Maze (MWM), (3) Delay Match to Place (DMP), and (4) Cue Strategy.
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影响因子:
5.3
作者:
Wisman, Liselijn A. B.;Sahin, Gurdal;Kirik, Deniz
通讯作者:
Kirik, Deniz
影响因子:
7.4
作者:
Ramanan S;Kooshki M;Zhao W;Hsu FC;Robbins ME
通讯作者:
Robbins ME
DOI:
10.4061/2011/689181
发表时间:
2011
期刊:
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影响因子:
--
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Carboni E
DOI:
10.1016/j.ijrobp.2009.06.059
发表时间:
2009-11-01
影响因子:
7
作者:
Ramanan, Sriram;Kooshki, Mitra;Zhao, Weiling;Hsu, Fang-Chi;Riddle, David R.;Robbins, Mike E.
通讯作者:
Robbins, Mike E.
影响因子:
4.9
作者:
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通讯作者:
Zhao, Yi