Healing of trabeculectomies in rabbits.
Healing of trabeculectomies in rabbits.
复制标题
兔子小梁切除术的愈合。
DOI：
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发表时间：
1979
影响因子：
4.2
通讯作者：
Morin Jd
中科院分区：
文献类型：
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作者：
A. Seetner;Morin Jd
我们研究了愈合小梁切除术在兔子的照片，荧光素过滤和组织切片。最初，除1家外，所有公司都开发了经过验证的过滤技术。然而，到第14天，结膜下、葡萄膜和巩膜的成纤维细胞增殖（和胶原蛋白产生）结合起来封闭瘘管。在手术时结膜下注射8 mg泼尼松龙治疗的眼睛组显示出轻微的伤口愈合延迟，但到第30天，治疗组和未治疗组之间几乎没有差异。接受类固醇治疗的眼睛出现了并发症，从1只眼睛的眼内炎到3只眼睛的组织坏死。
We studied the healing of trabeculectomies in rabbits with photographs, fluorescein filtration and histological sections. Initially all except 1 developed proven filtration. However, vigorous fibroblastic proliferation (and collagen production) from the subconjunctiva, uvea and sclera combined to close off the fistula by day 14. Groups of eyes treated with 8 mg of prednisolone injected subconjunctivally at operation showed slightly delayed wound healing but by day 30 there was little difference between treated and untreated groups. The steroid treated eyes had complications ranging from endophthalmitis in 1 eye to tissue necrosis in 3 eyes.