HEREDITARY DEAFNESS IN THE CAT - AN ELECTRON-MICROSCOPIC STUDY OF THE SPIRAL GANGLION
HEREDITARY DEAFNESS IN THE CAT - AN ELECTRON-MICROSCOPIC STUDY OF THE SPIRAL GANGLION
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DOI：
10.3109/00016488009131737
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发表时间：
1980-01-01
影响因子：
1.4
通讯作者：
MAIR, IWS
中科院分区：
文献类型：
--
作者：
ELVERLAND, HH;MAIR, IWS
对遗传性耳聋大白猫的脊神经节进行了透射电子显微镜观察，并与不同年龄的听力动物进行了比较。神经节细胞丢失继发于Corti器官的破坏，但仅在几个月后发生。在神经元丢失之前，I型神经节细胞失去了髓鞘，并同时产生了更多的神经丝。I型神经元通过中间的III型阶段转化为II型神经元。这种神经丝状变性的过程发生得很慢。吞噬作用显然是一种不明显的特征。
The spinal ganglion from white cats with hereditary deafness was studied by transmission electron microscopy and compared with hearing animals at different ages. Ganglion cell loss occurred secondary to destruction of the organ of Corti, but only after the lapse of several months. Prior to neuronal loss, the type I ganglion cells lost their myelin sheaths and concurrently developed an increased content of neurofilaments. Type I neurons transformed into type II through an intermediate type III stage. This process of neurofilamentous degeneration occurred slowly. Phagocytosis apparently is an inconspicuous feature.