Heterogeneous Rh and Rh/Ag bimetallic nanoparticle catalysts immobilized on chiral polymers
Heterogeneous Rh and Rh/Ag bimetallic nanoparticle catalysts immobilized on chiral polymers
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DOI：
10.1039/c9sc02670c
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发表时间：
2019-06
期刊：
影响因子：
8.4
通讯作者：
Hyemin Min;H. Miyamura;T. Yasukawa;S. Kobayashi
中科院分区：
文献类型：
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作者：
Hyemin Min;H. Miyamura;T. Yasukawa;S. Kobayashi
非均相手性催化剂虽然具有环境友好、可持续发展等优点，但其发展却远远落后于均相手性催化剂。本文描述了由具有手性二烯部分的聚苯乙烯基聚合物组成的新型非均相手性Rh和Rh/Ag纳米颗粒催化剂。该催化剂能够在芳基硼酸与α，β-不饱和羰基化合物如酮、酯和酰胺的不对称1，4-加成反应中以及在其它不对称反应中获得高至优异的产率和对映选择性。催化剂可以通过简单的过滤回收并重复使用，它们也可以用于连续流合成。我们还讨论了可能的反应物种的XPS分析的基础上的性质。
The development of heterogeneous chiral catalysts has lagged far behind that of homogeneous chiral catalysts in spite of their advantages, such as environmental friendliness for a sustainable society. We describe herein novel heterogeneous chiral Rh and Rh/Ag bimetallic nanoparticle catalysts consisting of polystyrene-based polymers with chiral diene moieties. The catalysts enable high-to-excellent yields and enantioselectivities to be obtained in asymmetric 1,4-addition reactions of arylboronic acids with α,β-unsaturated carbonyl compounds such as ketones, esters, and amides, and in other asymmetric reactions. The catalysts could be readily recovered by simple filtration and reused; they could also be applied to continuous-flow synthesis. We also discuss the nature of possible reaction species based on XPS analysis.