PLASMA FATTY-ACID COMPOSITION AS AN INDICATOR OF HABITUAL DIETARY-FAT INTAKE IN MIDDLE-AGED ADULTS
PLASMA FATTY-ACID COMPOSITION AS AN INDICATOR OF HABITUAL DIETARY-FAT INTAKE IN MIDDLE-AGED ADULTS
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DOI：
10.1093/ajcn/62.3.564
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发表时间：
1995-09-01
影响因子：
7.1
通讯作者：
ECKFELDT, JH
中科院分区：
文献类型：
--
作者：
MA, J;FOLSOM, AR;ECKFELDT, JH
用66项半定量食物频率问卷(FFQ)测定了3570名自由生活的中年人习惯性饮食的血浆脂肪酸(FA)组成，并与用气相色谱法测定的相应的血浆磷脂和胆固醇酯(CE)FA组成进行了比较。磷脂和CE的饱和脂肪酸(r=0.15和0.23)、单不饱和脂肪酸(r=0.05和0.01)、多不饱和脂肪酸(r=0.25、0.31)、亚油酸(r=0.22和0.28)、亚麻酸(r=0.15和0.21)、二十碳五烯酸(r=0.20和0.23)、二十二碳六烯酸(r=0.42和0.42)分别与饲料和血浆脂肪酸(占总脂肪酸的百分比)之间的Pearson相关关系。无论参与者是否超重、是否患有慢性病、是否饮酒或吸烟，饮食与血浆FAs之间的相关性都保持相对恒定。然而，在相似的膳食摄入量中，与没有这些特征的人相比，具有这些特征的人的饱和脂肪酸的血浆脂浓度更高和/或亚油酸的浓度更低。
We compared the plasma fatty acid (FA) composition of the habitual diet, measured by a 66-item semiquantitative food-frequency questionnaire (FFQ), with the corresponding plasma phospholipid and cholesterol ester (CE) FA composition measured by gas chromatography in 3570 free-living, middle-aged adults. Pearson correlations between dietary and plasma FA (expressed as % of total FAs) for phospholipid and CE, respectively, were as follows: saturated FA (r = 0.15 and 0.23), monounsaturated FA (r = 0.05 and 0.01), polyunsaturated FA (r = 0.25, 0.31), linoleic acid (r = 0.22 and 0.28), linolenic acid (r = 0.15 and 0.21), eicosapentaenoic acid (r = 0.20 and 0.23), and docosahexaenoic acid (r = 0.42 and 0.42). The correlations between diet and plasma FAs held relatively constant regardless of whether participants were overweight, had chronic diseases, were alcohol drinkers, or were cigarette smokers. However, at similar reported dietary intakes, the plasma lipid concentration of saturated FAs was higher and/or that of linoleic acid was lower in people with these characteristics compared with those without these characteristics.